Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-771) (CAT#: AFC-TAB-771)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human MS4A1/CD20. It is a humanized monoclonal antibody designed for the treatment of cancer and autoimmune disorders. The antibody is engineered for enhanced affinity to the CD20 antigen on B-lymphocytes, increased antibody-dependent cell-mediated cytotoxicity (ADCC), and for improved treatment of low-affinity FcγRIIIa allotypes.

Specific Inquiry
  • Size:
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  • Purity:
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  • Fc Engineering:
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC
  • Conjugate
  • Unconjugated
  • Generic Name
  • Ocaratuzumab
  • Related Disease
  • Non-Hodgkin's lymphoma (NHL)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16

Related Resources

  • Biosimilar Overview
Please refer to Ocaratuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ocaratuzumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Ocaratuzumab"

DrugMonitor™ Anti-Ocaratuzumab Antibody (VS-1224-YC829)
Ocaratuzumab, a humanized monoclonal antibody directed against CD20, is being explored for its efficacy in cancers and autoimmune disorders. The DrugMonitor™ Anti-Ocaratuzumab Antibody (VS-1224-YC829) is an anti-drug antibody (ADA) against Ocaratuzumab. This drug-based antibody is raised in mice immunized with the Ocaratuzumab. The anti-Ocaratuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ocaratuzumab in samples.

See other products for "MS4A1"

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TAB-1633CL Anti-Human MS4A1 Recombinant Antibody (ch1F5) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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