Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-772)

CAT#: AFC-TAB-772

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human MS4A1/CD20. It is a humanized anti-CD20 monoclonal antibody. It targets mature B lymphocytes and hence is an immunosuppressive drug candidate.

Gene Expression
Figure 1 IF staining of human cell line REH Figure 2 IF staining of human cell line A-431 Figure 3 IF staining of human cell line U-2 OS Figure 4 Colon Figure 5 Bone marrow Figure 6 Lymph node Figure 7 RNA cell line category: Group enriched (Daudi, U-698)

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • ELISA, IP, FC, FuncS, Neut, IF
  • Conjugate
  • Unconjugated
  • Generic Name
  • Ocrelizumab
  • Related Disease
  • Multiple sclerosis (MS) (relapsing remitting)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Ocrelizumab"

DrugMonitor™ Anti-Ocrelizumab Antibody (VS-1224-YC831)
Ocrelizumab is a monoclonal antibody targeting CD20, utilized in the management of relapsing-remitting multiple sclerosis. The DrugMonitor™ Anti-Ocrelizumab Antibody (VS-1224-YC831) is an anti-drug antibody (ADA) against Ocrelizumab. This drug-based antibody is raised in mice immunized with the Ocrelizumab. The anti-Ocrelizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ocrelizumab in samples.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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