Anti-Human MS4A1 Recombinant Antibody (ch1F5-DXL) (CAT#: TAB-1634CL)

This antibody chlF5-DXL binds to human CD20. The chlF5-DXL has the in vivo killing potential on tumor cells.

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FC

Figure 1 A comparison of binding of ch1F5 to DXL-ch1F5 to JOK-1 cells using FACS on fixed cells

Figure 1 A comparison of binding of ch1F5 to DXL-ch1F5 to JOK-1 cells using FACS on fixed cells

Apop

Figure 2 A comparison of induction of apoptosis by ch1F5 and DXL-ch1F5 on Raji (A-C) and Ramos (D-F) cells. Panels A and D cells only, B and E ch1F5, C and F DXL-ch1F5;

Figure 2 A comparison of induction of apoptosis by ch1F5 and DXL-ch1F5 on Raji (A-C) and Ramos (D-F) cells. Panels A and D cells only, B and E ch1F5, C and F DXL-ch1F5;

CDC

Figure 3 A comparison of CDC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Figure 3 A comparison of CDC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

ADCC

Figure 4 A comparison of ADCC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Figure 4 A comparison of ADCC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Inhib

Figure 5 A comparison of inhibition of proliferation, Panel A, Raji, B, Ramos, with ch1F5 and DXL-ch1F5.

Figure 5 A comparison of inhibition of proliferation, Panel A, Raji, B, Ramos, with ch1F5 and DXL-ch1F5.


Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Clone
  • ch1F5-DXL
  • Applications
  • FC, Apop, CDC, ADCC, Inhib
  • Related Disease
  • Chronic diseases, such as cancer and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, Apoptosis, Complement-dependent Cytotoxicity Assay, Antibody-dependent Cellular Cytotoxicity Assay and Inhibition.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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