Anti-Human MS4A1 Recombinant Antibody (ch1F5-DXL) (CAT#: TAB-1634CL)

This antibody chlF5-DXL binds to human CD20. The chlF5-DXL has the in vivo killing potential on tumor cells.


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FC

Figure 1 A comparison of binding of ch1F5 to DXL-ch1F5 to JOK-1 cells using FACS on fixed cells

Figure 1 A comparison of binding of ch1F5 to DXL-ch1F5 to JOK-1 cells using FACS on fixed cells

Apop

Figure 2 A comparison of induction of apoptosis by ch1F5 and DXL-ch1F5 on Raji (A-C) and Ramos (D-F) cells. Panels A and D cells only, B and E ch1F5, C and F DXL-ch1F5;

Figure 2 A comparison of induction of apoptosis by ch1F5 and DXL-ch1F5 on Raji (A-C) and Ramos (D-F) cells. Panels A and D cells only, B and E ch1F5, C and F DXL-ch1F5;

CDC

Figure 3 A comparison of CDC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Figure 3 A comparison of CDC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

ADCC

Figure 4 A comparison of ADCC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Figure 4 A comparison of ADCC using ch1F5 and DXL-ch1F5. Panel A, Raji, B, Ramos.

Inhib

Figure 5 A comparison of inhibition of proliferation, Panel A, Raji, B, Ramos, with ch1F5 and DXL-ch1F5.

Figure 5 A comparison of inhibition of proliferation, Panel A, Raji, B, Ramos, with ch1F5 and DXL-ch1F5.


Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Clone
  • ch1F5-DXL
  • Applications
  • FC, Apop, CDC, ADCC, Inhib
  • Related Disease
  • Chronic diseases, such as cancer and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, Apoptosis, Complement-dependent Cytotoxicity Assay, Antibody-dependent Cellular Cytotoxicity Assay and Inhibition.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Chimeric Antibody

CAT Product Name Application Type
TAB-016 Anti-Human CD20 Recombinant Antibody (Rituximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-207 Anti-Human CD20 Recombinant Antibody ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1 - kappa
TAB-1675CL-S(P) Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1675CL-S(P)) ELISA, WB Mouse scFv
TAB-1692CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (Zytux) ELISA, WB Chimeric antibody (mouse/human)
TAB-1700CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (R92-3-1) ADCC Chimeric antibody (mouse/human)

Recombinant Antibody

Humanized Antibody

Fc Glycosylation

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-771 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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