This antibody directed to the antigen CD20 is useful for inhibiting the growth of cells that express CD20. The 2.1.2 antibody mediates great cell lysis as demonstrated in the Raji cell line.
Figure 1 shows the results of cell viability assays without cross-linking of Ramos cells incubated with the antibody, and the Rituxan® ("Rituximab") antibody control.
Percent viability of Ramos cells is shown on the y-axis and antibody concentration is shown on the x-axis.
Figure 2 shows the results of Annexin V/PI apoptosis assays without cross-linker of Ramos cells incubated with mAbs.
Rituximab and Bl. % viability is shown on the y-axis and antibody concentration is on the x-axis.
Figure 3 shows the results of CDC assays of Ramos cell lines, respectively, incubated with mAbs.
Figure 4 is a graph shows results of an ADCC assay of Ramos cell line incubated with mAbs 2.1.2, 1.1-2, 1.5.3, 1.10.3.1, and 1.11.3.1, Rituximab, and IgGl control. % viability is showsn on the y-axis and antibody concentration is showsn on the x-axis.
Figure 5 is a line graph shows the effect of anti-CD20 antibodies, Rituximab, 2.1.2, 1.1.2, and 1.5.3 on mouse survival in a Ramos i.v. paralysis model (CB 17 SCID).
The results show that three anti-CD20 antibodies demonstrate potent anti- lymphoma activity when administered as a single dose monotherapy. The number of days of treatment post tumor cell implantation is shown on the x-axis and percent survival is shown on the y-axis.
Figure 6 is a line graph shows the efficacy of anti-CD20 antibodies in the Daudi subcutaneous tumor model.
The number of days of treatment after the time of tumor cell inoculation is shown on the x-axis and tumor volume in cubic millimeters is shown on the y-axis.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-913-sdAb | Recombinant Anti-human MS4A1 VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
HPAB-M0704-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD25) | ELISA, FuncS | Camelid VHH |
HPAB-M0705-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD16) | ELISA | Camelid VHH |
HPAB-M0706-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone R3CD7) | ELISA | Camelid VHH |
HPAB-M0707-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD78) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-772 | Human Anti-MS4A1 Recombinant Antibody (TAB-772) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 |
TAB-771 | Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized IgG1, κ |
TAB-1638CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) | ADCC, CDC | Humanized IgG |
TAB-1639CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) | ADCC, CDC, Apop | Humanized IgG |
TAB-1640CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) | ADCC, CDC, Apop, FuncS | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H27 | Anti-Human MS4A1 Recombinant Antibody (Epitumomab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG2a |
TAB-1657CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K1422) | Apop, FuncS | |
TAB-1658CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K1791) | Apop, FuncS | |
PABX-026-S (P) | Recombinant Mouse Anti-CD20 Antibody scFv Fragment (C2H7) | WB, ELISA, FuncS | scFv |
PABX-028-S (P) | Recombinant Human Anti-CD20 Antibody scFv Fragment (Ofatumumab) | WB, ELISA, IF, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-143 | Mouse Anti-MS4A1 Recombinant Antibody (clone KM3575); scFv Fragment | WB | Mouse scFv |
FAMAB-0144-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone C2B8); Fab Fragment | WB, ELISA | Chimeric (mouse/human) Fab |
HPAB-0018-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0018-FY-F(E)) | FC | Humanized Fab |
HPAB-0021-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone hu3D9); Fab Fragment | FC | Humanized Fab |
HPAB-0819-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone 1F5RKF12); Fab Fragment | ELISA, FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0001CL | Human Anti-MS4A1 Recombinant Antibody (TAB-0001CL) | ELISA, ADCC, CDC | Human IgG |
TAB-1648CL-F(E) | Anti-MS4A1 Recombinant Antibody Fab Fragment (MEDI-552) | Inhib | |
TAB-1654CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1654CL-F(E)) | FC, Apop | Human Fab |
TAB-1655CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1655CL-F(E)) | ELISA | Human Fab |
PABX-028 | Recombinant Human Anti-CD20 Antibody (Ofatumumab) | WB, ELISA, IF, FuncS, Apop, BA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1665CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1665CL-S(P)) | CDC | Mouse scFv |
TAB-1666CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1666CL-S(P)) | CDC | Mouse scFv |
TAB-1667CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1667CL-S(P)) | CDC | Mouse scFv |
TAB-1668CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1668CL-S(P)) | CDC | Mouse scFv |
TAB-1669CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1669CL-S(P)) | CDC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-115LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Gly-134LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-154LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Gly-155LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated | ELISA | Humanized antibody |
Gly-158LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-134LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-135LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-136LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-137LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-138LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-142LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-155LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-171LC | Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC066 | PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC067 | APC-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC068 | BV421-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC4347 | PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1751CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) | Neut, FuncS | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2295 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB) | IHC-Fr, IHC-P | Rabbit IgG |
MOR-4024 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-027CQ | Human Anti-MS4A1 Recombinant Antibody (clone CBLS-185) | Neut, FuncS | Human IgG1, κ |
HPAB-0018-FY | Human Anti-MS4A1 Recombinant Antibody (HPAB-0018-FY) | FC | Humanized IgG1 |
HPAB-0021-FY | Human Anti-MS4A1 Recombinant Antibody (clone hu3D9) | FC | Humanized IgG |
MRO-0288-CN | Rabbit Anti-MS4A1 Recombinant Antibody (clone CBACN-109) | WB, IHC, IP | Rabbit IgG |
HPAB-0702-FY | Mouse Anti-MS4A1 Recombinant Antibody (clone AB001) | FC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0683-CN-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut8); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-0684-CN-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut5); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1585-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1585-FY-F(E)) | ELISA, FC | Mouse Fab |
HPAB-1885-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1885-FY-F(E)) | ELISA, FC | Human Fab |
HPAB-1954-FY-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone BD31-7); scFv Fragment | Cyt | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-772 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-016 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-028 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-207 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-771 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
There are currently no Customer reviews or questions for TAB-1645CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.