Anti-Human CD20 Recombinant Antibody (Rituximab) (CAT#: TAB-016)

Recombinant monoclonal antibody to Human CD20. Rituximab (trade names rituximab and rituximab) is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells). Rituximab destroys B cells and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. This includes many lymphomas, leukemias, transplant rejection, and autoimmune disorders.


Specific Inquiry
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WB

Figure 1 Anti-CD20 Antibody (TAB-016) in WB

Figure 1 Anti-CD20 Antibody (TAB-016) in WB

Western blot analysis of TAB-016 was performed with CD20 Protein, Human, Recombinant (TrxA Tag).
TAB-016 incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing Antigen (0.1μg)
Lane 2: Reducing Antigen (0.3μg)
Lane 3: Reducing Antigen (0.6μg)

FC

Figure 2 Anti-CD20 Antibody (TAB-016) in Flow Cytometry

Figure 2 Anti-CD20 Antibody (TAB-016) in Flow Cytometry

Flow cytometry analysis of Daudi cells with Anti-CD20 Antibody (Cat#TAB-016, Blue line) or isotype control antibody (Yellow line). A Goat Anti-human IgG (FITC) was used as the secondary antibody.


Specifications

  • Immunogen
  • Human lymphoblastoid cell line SB
  • Host Species
  • Mouse
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • IgG1 - kappa
  • Specificity
  • Tested positive against native human antigen
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, WB and most other immunological methods.
  • Trade name
  • rituximab / rituximab
  • CAS
  • 174722-31-7
  • Generic Name
  • Rituximab
  • Biological Half-Life
  • 30 to 400 hours (varies by dose and length of treatment)
  • ATC Code
  • L01XC02
  • DrugBank
  • DB00073
  • UNII
  • 4F4X42SYQ6
  • ChEMBL
  • CHEMBL1201576
  • MW
  • 143,859.7 g/mol
  • Related Disease
  • Wegener's Granulomatosis (WG) and Microscopic Polygamiitis (MPA), in combination with glucocorticoides

Product Property

  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Target

  • Alternative Names
  • Rituximab;rituximab / rituximab;174722-31-7;rituximab;rituximab;rituximab;Zytux;DB00073MS4A1;membrane-spanning 4-domains, subfamily A, member 1;CD20;B-lymphocyte antigen CD20;B1;Bp35;CD20 antigen;CD20 receptor;leukocyte surface antigen Leu-16;B-lymphocyte c

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Rituximab"

Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human CD20. Rituximab (trade names rituximab and rituximab) is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells). Rituximab destroys B cells and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. This includes many lymphomas, leukemias, transplant rejection, and autoimmune disorders.

See other products for "MS4A1"

Humanized Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-1665CL Human Anti-MS4A1 Recombinant Antibody (TAB-1665CL) CDC Chimeric (mouse/human) IgG
TAB-1666CL Human Anti-MS4A1 Recombinant Antibody (TAB-1666CL) CDC Chimeric (mouse/human) IgG
TAB-1667CL Human Anti-MS4A1 Recombinant Antibody (TAB-1667CL) CDC Chimeric (mouse/human) IgG
TAB-1668CL Human Anti-MS4A1 Recombinant Antibody (TAB-1668CL) CDC Chimeric (mouse/human) IgG
TAB-1669CL Human Anti-MS4A1 Recombinant Antibody (TAB-1669CL) CDC Chimeric (mouse/human) IgG

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-771 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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