Products

Rituximab (TAB-016)

Recombinant monoclonal antibody to Human CD20. Rituximab (trade names rituximab and rituximab) is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells). Rituximab destroys B cells and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. This includes many lymphomas, leukemias, transplant rejection, and autoimmune disorders.      

  • Datasheet

Specifications
Immunogen
Human lymphoblastoid cell line SB
Host
Mouse
Derivation
Chimeric (mouse/human)
Type
IgG1 - kappa
Specificity
Tested positive against native human antigen
Species Reactivity
Human
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, WB and most other immunological methods.
Trade name
rituximab / rituximab
CAS NO.
174722-31-7
Generic Name
Rituximab
Biological Half-Life
30 to 400 hours (varies by dose and length of treatment)
ATC Code
L01XC02
DrugBank
DB00073
UNII
4F4X42SYQ6
ChEMBL
CHEMBL1201576
M.W.
143,859.7 g/mol
Related Disease
Wegener's Granulomatosis (WG) and Microscopic Polygamiitis (MPA), in combination with glucocorticoides
Target
Alternative Names
Rituximab; rituximab / rituximab; 174722-31-7; rituximab; rituximab; rituximab; Zytux; DB00073MS4A1
Entrez Gene ID
931
UniProt ID
P11836

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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