Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-028)

CAT#: AFC-TAB-028

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human CD20. It is a human monoclonal antibody (for the CD20 protein) which appears to inhibit early-stage B lymphocyte activation.

Gene Expression
Figure 1 IF staining of human cell line REH Figure 2 IF staining of human cell line A-431 Figure 3 IF staining of human cell line U-2 OS Figure 4 Colon Figure 5 Bone marrow Figure 6 Lymph node Figure 7 RNA cell line category: Group enriched (Daudi, U-698)

Specifications

  • Immunogen
  • Hmuan CD20 transfected NS/O cells.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • FC, IP, ELISA, Neut, FuncS, IF
  • Conjugate
  • Unconjugated
  • Trade name
  • Arzerra
  • Generic Name
  • Ofatumumab
  • Related Disease
  • Rheumatoid arthritis (RA)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16
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Biosimilar Overview

Please refer to Ofatumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ofatumumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Ofatumumab"

DrugMonitor™ Anti-Ofatumumab Antibody (VS-1224-YC836)
Ofatumumab is an anti-CD20 antibody used in the treatment of chronic lymphocytic leukemia (CLL) for patients with particular treatment histories and specific responsiveness to anticancer therapies. The DrugMonitor™ Anti-Ofatumumab Antibody (VS-1224-YC836) is an anti-drug antibody (ADA) against Ofatumumab. This drug-based antibody is raised in mice immunized with the Ofatumumab. The anti-Ofatumumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ofatumumab in samples.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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