Recombinant human antibody to Env. 13.6A can neutralize HIV-1 isolates.
Figure 1 Neutralization profile of 205F Envs by autologous monoclonal antibody-containing supernatants from B cell hybridomas 13.6A.
Neutralization activity of 13.6A (B) B cell hybridoma supernatant was evaluated against pseudoviruses expressing autologous 205F Envs.
Rong, R., Li, B., Lynch, R. M., Haaland, R. E., Murphy, M. K., Mulenga, J., ... & Robinson, J. E. (2009). Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. PLoS pathogens, 5(9).
Figure 2 Potential N-linked glycosylation sites in V1 and V2 modulate sensitivity to Mabs.
Neutralization of 0-month EnvPL6.3 and the sitedirected mutants shown in panel B was evaluated for 13.6A using reduction of luciferase production in JC53-BL13 cells.
Rong, R., Li, B., Lynch, R. M., Haaland, R. E., Murphy, M. K., Mulenga, J., ... & Robinson, J. E. (2009). Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. PLoS pathogens, 5(9).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-474-S(P) | Recombinant Anti-HIV-1 Env Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
PSBC-420 | Human Anti-HIV-1 Env Recombinant Antibody (clone CAP228-3D); scFv Fragment | Neut | Human scFv |
HPAB-0122-WJ-S(P) | Human Anti-HIV-1 Env Recombinant Antibody (clone B358.II); scFv Fragment | ELISA, WB | Human scFv |
PABJ-0039-S(P) | Human Anti-HIV-1 Env Recombinant Antibody (clone 1-55); scFv Fragment | ELISA, Neut | Human scFv |
PABJ-0053-S(P) | Human Anti-HIV-1 Env Recombinant Antibody (clone 1-18); scFv Fragment | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-057 | Recombinant Anti-HIV-1 env VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-381 | Human Anti-HIV-1 Env Recombinant Antibody (clone VRC07) | WB, ELISA, FuncS | Human IgG1 |
PABL-514 | Human Anti-HIV-1 Env Recombinant Antibody (clone 17B) | FC, Neut | Human IgG1 |
PABL-516 | Monkey Anti-HIV-1 Env Recombinant Antibody (clone GE356) | WB, ELISA, FuncS | Monkey IgG |
PABL-519 | Human Anti-HIV-1 Env Recombinant Antibody (PABL-519) | Neut | Human IgG |
MRO-2742CQ | Human Anti-HIV-1 Env Recombinant Antibody (clone 10.9D) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-2742CQ-F(E) | Human Anti-HIV-1 Env Recombinant Antibody (clone 10.9D); Fab Fragment | ELISA | Human Fab |
MRO-2770CQ-F(E) | Human Anti-HIV-1 Env Recombinant Antibody (clone 3BNC53); Fab Fragment | Neut | Human Fab |
MRO-2771CQ-F(E) | Human Anti-HIV-1 Env Recombinant Antibody (clone 3BNC66); Fab Fragment | Neut | Human Fab |
MRO-2772CQ-F(E) | Human Anti-HIV-1 Env Recombinant Antibody (clone 3BNC72); Fab Fragment | Neut | Human Fab |
MRO-2773CQ-F(E) | Human Anti-HIV-1 Env Recombinant Antibody (clone 6.4C); Fab Fragment | Neut | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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