Recombinant human antibody to gp120. The antibody can bind to the JR-FL SOSIP trimer, and poorly or not at all to gp120 monomer. It was highly dependent on the N301 and N332 glycans.
Figure 1 Donor N170 antibodies bind better to JRFL SOSIP gp140 than to JRFL gp120.
ELISA for binding to JRFL SOSIP gp140 or gp120 of donor N170 antibody VRC29.02. Graphs are representative of results from at least two independent experiments. OD, optical density.
Longo, N. S., Sutton, M. S., Shiakolas, A. R., Guenaga, J., Jarosinski, M. C., Georgiev, I. S., ... & Connors, M. (2016). Multiple antibody lineages in one donor target the glycan-V3 supersite of the HIV-1 envelope glycoprotein and display a preference for quaternary binding. Journal of virology, 90(23), 10574-10586.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
NABG-082 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABZ-060 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 50.1) | Neut | Mouse IgG2a, κ |
PABZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody (PABZ-164) | ELISA, Neut | Human IgG |
PABZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01) | Neut | Human IgG |
PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-46M2) | ELISA, Neut | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-041LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (D59/A2) | ELISA | Mouse antibody |
MRO-042LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (F58/H3) | ELISA | Mouse antibody |
MRO-043LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (P1/D12) | ELISA | Mouse antibody |
MRO-044LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (P4/D10) | ELISA | Mouse antibody |
MRO-045LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (A47/B1) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-3155CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone F530); Fab Fragment | ELISA, Neut | Human Fab |
MRO-3156CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone F91 (F-91)); Fab Fragment | ELISA, Neut | Human Fab |
MRO-3157CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone HGD14); Fab Fragment | ELISA, Neut | Human Fab |
MRO-3158CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone HGF12); Fab Fragment | ELISA | Human Fab |
MRO-3159CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone HGF9); Fab Fragment | ELISA, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-S0050-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3792); scFv Fragment | ELISA | Human scFv |
HPAB-S0052-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone MAb 2158); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-1990-FY-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 16c); scFv Fragment | WB | Human scFv |
HPAB-1991-FY-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 23e); scFv Fragment | WB | Human scFv |
FAMAB-0058WJ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone P20); scFv Fragment | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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