This product is a recombinant human anti-HIV-1 monoclonal antibody. 2556 (213Bi-2556) specifically binds to gp160(592-603).
Figure 1 Inhibition of binding of biotinylated anti-gp41 mAbs to JR-CSF transfected 293T cells by serum from HIV-1 infected individuals.
Characterization of 2556 mAb specificity.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Figure 2 ELISA reactivity to recombinant gp41MN of 2556 CHROMOS and 2556 derived from original NYU hybridoma.
246D is an anti-gp41 mAb and 1418 is a negative control.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Figure 3 The binding of ‘‘cold’’ 2556 to chronically-infected ACH-2 cells by flow cytometry.
HIV-1-negative A3.01 cells were used as controls.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-177) | WB, ELISA, Neut, FuncS | Human IgG |
PABL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L) | WB, ELISA, FuncS | Human IgG |
PABL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) | WB, ELISA, FuncS | Human IgG |
PABL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C) | WB, ELISA, Neut, FuncS | Human IgG, κ |
PABL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01) | FC, Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08); scFv Fragment | Neut, FuncS | Human scFv |
PFBC-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2558); Fab Fragment | ELISA, Neut | Human Fab |
MRO-3946CQ-S(P) | Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone G3-211); scFv Fragment | Neut, IF | Mouse scFv |
MRO-3947CQ-S(P) | Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 1578); scFv Fragment | ELISA | Mouse scFv |
PSBC-305 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBC-305) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08); Fab Fragment | Neut, FuncS | Human Fab |
PFBL-551 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01); Fab Fragment | Neut | Human Fab |
PFBL-552 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02); Fab Fragment | Neut | Human Fab |
PFBL-553 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-553) | Neut | Human Fab |
PFBL-554 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone Z258-VRC27.01); Fab Fragment | Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-075LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (24G3) | ELISA | Human antibody |
MRO-080LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (81C7) | ELISA | Human antibody |
MRO-091LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (MAb CL1) | ELISA | Human antibody |
MRO-075LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (24G3) | ELISA | Human antibody |
MRO-080LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (81C7) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-086LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1C1) | ELISA | Mouse antibody |
MRO-087LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1H9) | ELISA | Mouse antibody |
MRO-088LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (2D7) | ELISA | Mouse antibody |
MRO-086LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1C1) | ELISA | Mouse antibody |
MRO-087LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1H9) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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