Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2556 (213Bi-2556)) (CAT#: MRO-3773CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. 2556 (213Bi-2556) specifically binds to gp160(592-603).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Inhibition of binding of biotinylated anti-gp41 mAbs to JR-CSF transfected 293T cells by serum from HIV-1 infected individuals.
Characterization of 2556 mAb specificity.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Figure 2 ELISA reactivity to recombinant gp41MN of 2556 CHROMOS and 2556 derived from original NYU hybridoma.
246D is an anti-gp41 mAb and 1418 is a negative control.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Figure 3 The binding of ‘‘cold’’ 2556 to chronically-infected ACH-2 cells by flow cytometry.
HIV-1-negative A3.01 cells were used as controls.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Recognizes HIV-1 gp160(592-603)
- Species Reactivity
- HIV-1
- Clone
- 2556 (213Bi-2556)
- Applications
- ELISA, FC, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08) | Neut, FuncS | Human IgG, κ |
PABL-554 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01) | FC, Neut | Human IgG |
PABL-555 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02) | FC, Neut | Human IgG |
PABL-556 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-556) | Neut | Human IgG |
PABL-557 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone Z258-VRC27.01) | FC, Neut | Human IgG |
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