Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2556 (213Bi-2556)) (CAT#: MRO-3773CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. 2556 (213Bi-2556) specifically binds to gp160(592-603).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 Inhibition of binding of biotinylated anti-gp41 mAbs to JR-CSF transfected 293T cells by serum from HIV-1 infected individuals.
Characterization of 2556 mAb specificity.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
ELISA
Figure 2 ELISA reactivity to recombinant gp41MN of 2556 CHROMOS and 2556 derived from original NYU hybridoma.
246D is an anti-gp41 mAb and 1418 is a negative control.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
FC
Figure 3 The binding of ‘‘cold’’ 2556 to chronically-infected ACH-2 cells by flow cytometry.
HIV-1-negative A3.01 cells were used as controls.
Dadachova, E., Kitchen, S. G., Bristol, G., Baldwin, G. C., Revskaya, E., Empig, C., ... & Casadevall, A. (2012). Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication. PloS one, 7(3).
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Recognizes HIV-1 gp160(592-603)
- Species Reactivity
- HIV-1
- Clone
- 2556 (213Bi-2556)
- Applications
- ELISA, FC, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Human Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-554 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01) | FC, Neut | Human IgG |
| PABL-555 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02) | FC, Neut | Human IgG |
| PABL-556 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-556) | Neut | Human IgG |
| PABL-557 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone Z258-VRC27.01) | FC, Neut | Human IgG |
| MRO-3769CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 1131-A) | FC | Human IgG3, λ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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