Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8-10fH/4fL) (CAT#: MRO-4138CQ)
Recombinant human antibody to gp41. This is a variant of 10E8, consisting of 10 H chain/4 L chain framework mutations. This variant neutralized 20/21 Envs.
Specific Inquiry
SDS-PAGE
Figure 1 Human Anti-HIV-1 gp41 Recombinant Antibody (MRO-4138CQ) in SDS-PAGE
SDS-PAGE analysis of MRO-4138CQ in β-mercaptoethanol-reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, the different reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of MRO-4138CQ was greater than 95% as determined by SDS-PAGE.
DB
Figure 2 Human Anti-HIV-1 gp41 Recombinant Antibody (MRO-4138CQ) in DB
Dot Blot analysis of MRO-4138CQ was performed by coating with recombinant HIV1 gp41 protein (His tag).
MRO-4138CQ incubation concentration: 2 μg/mL.
HRP conjugated Anti-Human IgG as a secondary antibody (1: 2000)
ELISA
Figure 3 Human Anti-HIV-1 gp41 Recombinant Antibody (MRO-4138CQ) in ELISA
ELISA analysis of MRO-4138CQ was performed by coating with recombinant HIV1 gp41 protein (His tag). Then blocked with BSA and incubated with MRO-4138CQ. The HRP conjugated Anti-Human IgG as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Recognizes HIV-1 gp41
- Species Reactivity
- HIV-1
- Clone
- 10E8-10fH/4fL
- Applications
- Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-025LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG3) | ELISA | Human antibody |
| MRO-026LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG1) | ELISA | Human antibody |
| MRO-040LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (M66.6) | ELISA | Human antibody |
| MRO-074LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (W) | ELISA | Human antibody |
| MRO-093LC-F(E) | Anti-HIV-1 gp41 Recombinant Antibody Fab Fragment (clone 43) | ELISA | Human antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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