Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 17C8) (CAT#: MRO-4170CQ)
Recombinant mouse antibody to gp41. 17C8 bound strongly to the N36/C34 but did not bind to the isolated peptides N36 and C34, indicating that this Ab is specific for the gp41 6-HB core.
Specific Inquiry
ELISA
Figure 1 Effects of MTSC22-induced mutations on the conformation of 6-HB structure.
The reactivity of 6-HBs formed by N36 and C34 or their mutants with conformation-dependent MAbs 17C8 .
Su, Y., Chong, H., Xiong, S., Qiao, Y., Qiu, Z., & He, Y. (2015). Genetic pathway of HIV-1 resistance to novel fusion inhibitors targeting the Gp41 pocket. Journal of virology, 89(24), 12467-12479.
Specifications
- Immunogen
- The N36(L8)C34 polypeptide where the N36- terminus is connected by a linker to the C34 N-terminus
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Recognizes HIV-1 gp41
- Species Reactivity
- HIV-1
- Clone
- 17C8
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 17C8"
See other products for "HIV-1 gp41"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-486-S(P) | Recombinant Anti-HIV-1 gp41 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| MHH-486-S(P) | Recombinant Human Anti-HIV-1 gp41 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MRO-4083CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone S8); scFv Fragment | ELISA | Human scFv |
| MRO-4084CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone S9); scFv Fragment | ELISA | Human scFv |
| MRO-4085CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone H2136-L773); scFv Fragment | ELISA, WB, FC | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
| PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
| PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
| PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
| PABL-189 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone m66) | Neut, FuncS | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
| PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
| PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
| MRO-4088CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HGH8); Fab Fragment | ELISA | Human Fab |
| MRO-4089CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HGN158); Fab Fragment | ELISA | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-025LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG3) | ELISA | Human antibody |
| MRO-026LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG1) | ELISA | Human antibody |
| MRO-040LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (M66.6) | ELISA | Human antibody |
| MRO-074LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (W) | ELISA | Human antibody |
| MRO-077LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (3D6) | ELISA | Human antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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