Human Anti-HIV gp120 Recombinant Antibody (clone SF12) (CAT#: FAMAB-0177WJ)
This product is a human antibody bind a distinct epitope on the gp120 Portion of Env. This antibody can be used in applications, such as ELISA, WB, Neut.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 ELISA of SF5 and SF12 against a gp120 monomer and a gp140 foldon trimer derived from HIV-1 strain YU2.
Wild-type proteins and various site mutants of the proteins in common bNAb epitopes (CD4-binding site, V3-glycan, Apex) were tested.
Schoofs, T., Barnes, C. O., Suh-Toma, N., Golijanin, J., Schommers, P., Gruell, H., West, A. P., Jr, Bach, F., Lee, Y. E., Nogueira, L., Georgiev, I. S., Bailer, R. T., Czartoski, J., Mascola, J. R., Seaman, M. S., McElrath, M. J., Doria-Rose, N. A., Klein, F., Nussenzweig, M. C., & Bjorkman, P. J. (2019). Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50(6), 1513–1529.e9.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HIV gp120
- Species Reactivity
- HIV
- Clone
- SF12
- Applications
- ELISA, WB, Neut
- Related Disease
- HIV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Human immunodeficiency virus; HIV
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-412 | Recombinant Anti-HIV gp120 Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-412 | Recombinant Human Anti-HIV gp120 Antibody | WB, Dot, FuncS | IgG |
| PABL-510 | Human Anti-HIV gp120 Recombinant Antibody (PABL-510) | ELISA, Neut | Human IgG1 |
| FAMAB-0080WJ | Human Anti-HIV gp120 Recombinant Antibody (clone NO.13) | ELISA, WB | Human IgG1, λ |
| FAMAB-0081WJ | Human Anti-HIV gp120 Recombinant Antibody (clone S1-1) | ELISA, WB | Human IgG1, λ |
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For Research Use Only. Not For Clinical Use.
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