Afuco™ Anti-IL17RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-217) (CAT#: AFC-TAB-217)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL17RA. It is a humanized monoclonal antibody used in the treatment of autoimmune diseases.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
Figure 3 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
Figure 4 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Ixekizumab
- Related Disease
- Psoriasis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;
- Gene ID
- 23765
- UniProt ID
- Q96F46
Related Resources
Please refer to Ixekizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ixekizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Ixekizumab"
DrugMonitor™ Anti-Ixekizumab Antibody (VS-1224-YC622)Ixekizumab is a humanized IgG4 monoclonal antibody against interleukin-17A (IL-17A), preventing interaction with IL-17A receptors, approved for treating moderate-to-severe plaque psoriasis in adults. The DrugMonitor™ Anti-Ixekizumab Antibody (VS-1224-YC622) is an anti-drug antibody (ADA) against Ixekizumab. This drug-based antibody is raised in mice immunized with the Ixekizumab. The anti-Ixekizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ixekizumab in samples.
See other products for "IL17RA"
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IgG Antibody Products
Single Domain Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2670z | Mouse Anti-IL17RA Recombinant Antibody (clone 42A2) | WB, FC, Neut | Mouse IgG1 |
| HPAB-0318-WJ | Human Anti-IL17RA Recombinant Antibody (HPAB-0318-WJ) | ELISA, Neut | Humanized IgG |
| HPAB-0319-WJ | Human Anti-IL17RA Recombinant Antibody (HPAB-0319-WJ) | ELISA, Neut | Humanized IgG |
| HPAB-1557-FY | Human Anti-IL17RA Recombinant Antibody (HPAB-1557-FY) | FC, Inhib | Human IgG |
| VS-0723-WK267 | Rabbit Anti-IL17RA Recombinant Antibody (VS-0723-WK267) | ELISA, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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