Mouse Anti-NFKB1 Recombinant Antibody (clone 4D11)
CAT#: VS3-WK1607
This antibody is a mouse recombinant antibody against human NFKB1, which is a 105 kD protein that can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The clone 4D11 can be used in WB analysis at a dilution of 1/1000-1/2000 and IHC analysis at a dilution of 1/50-1/200.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27305/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4031/11361_A_9_8.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4031/11361_A_9_3.jpg
RNA Expression
Figure 4 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109320-NFKB1
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Specifications
- Immunogen
- Synthesized peptide derived from human NF κB P105/P50
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human NFKB1
- Species Reactivity
- Human, Mouse
- Clone
- 4D11
- Applications
- IHC-P, WB
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 0.5% BSA, 50% Glycerol
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC-P: 1/50-1/200
WB: 1/1000-1/2000
Target
- Alternative Names
- Nuclear Factor Kappa B Subunit 1; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1; DNA-Binding Factor KBF1; EBP-1; Nuclear Factor Kappa-B DNA Binding Subunit; Nuclear Factor NF-Kappa-B P105 Subunit; Nuclear Factor NF-Kappa-B P50 Subunit; NF-Kappabeta; NF-Kappa-B; NF-KappaB
- Gene ID
- 4790
- UniProt ID
- P19838
- Long Name
- Nuclear Factor Kappa B Subunit 1
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Generation of the NF-kappa-B p50 (Nuclear factor NF-kappa-B p50 subunit) transcription factor takes place both cotranslationally and post-translationally via non-mutually exclusive mechanisms.
- Protein Refseq
- NP_001158884.1
- Function
- NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
Isotype Control
- CAT
- Product Name
See other products for "NFKB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1566z | Mouse Anti-NFKB1 Recombinant Antibody (clone 31H12) | WB, IF, IHC | Mouse IgG1 |
| MOB-1711MZ | Recombinant Mouse Anti-Human NFKB1 Antibody | IHC-P, WB | Mouse antibody |
| MRO-1091-CN | Recombinant Rabbit Anti-NFKB1 Monoclonal Antibody (CBACN-400) | WB, IHC | Rabbit IgG |
| ZG-0312C | Mouse Anti-NFKB1 Recombinant Antibody (ZG-0312C) | WB | Mouse IgG |
| VS3-FY2819 | Mouse Anti-NFKB1 Recombinant Antibody (VS3-FY2819) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0391MZ | Chicken Anti-NFKB1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2433 | Hi-Affi™ Recombinant Rabbit Anti-NFKB1 Monoclonal Antibody (DS2433AB) | WB, IHC-P, ICC, FC | IgG |
| MOR-4511 | Hi-Affi™ Recombinant Rabbit Anti-NFKB1 Monoclonal Antibody (TH19DS) | WB, FC | IgG |
| MOR-0096-FY | Rabbit Anti-NFKB1 Recombinant Antibody (clone AFY0067) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1090-CN | Recombinant Mouse Anti-NFKB1 Monoclonal Antibody (A2-7) | WB, IF, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4817 | Anti-NFKB1 Immunohistochemistry Kit | IHC |
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