AbPlus™ Anti-SIRPA Magnetic Beads (VS-0724-YC1462)
CAT#: VS-0724-YC1462
The AbPlus Anti-SIRPA Magnetic Beads (VS-0724-YC1462) is an innovative affinity resin which is bound with anti-SIRPA specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SIRPA protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2776/6761_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Endocrine cells
Staining:Medium
Intensity: Moderate
Enterocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2776/6761_A_7_3.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2776/6761_A_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (fHDF/TERT166, RPTEC TERT1, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198053-SIRPA
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SIRPA specific antibody
- Target
- SIRPA
- Immunogen
- Recombinant human SIRPA, aa 1-370.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
- Alternative Names
- Signal Regulatory Protein Alpha; CD172 Antigen-Like Family Member A; Inhibitory Receptor SHPS-1; Macrophage Fusion Receptor; PTPNS1; SHPS1; SIRP; P84; BIT; MFR; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; Tyrosine Phosphatase SHP Substrate 1; Signal-Regulatory Protein Alpha-1;
- Gene ID
- 140885
- UniProt ID
- P78324
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Sirpa"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1201-VHH | Recombinant Anti-Mouse Sirpa VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-453CT | Human Anti-SIRPA Recombinant Antibody (TAB-453CT) | Cyt, IF, FC | Chimeric (mouse/human) IgG4 |
| TAB-453CT-S(P) | Human Anti-SIRPA Recombinant Antibody; scFv Fragment (TAB-453CT-S(P)) | WB, ELISA | Human scFv |
| TAB-453CT-F(E) | Human Anti-SIRPA Recombinant Antibody; Fab Fragment (TAB-453CT-F(E)) | WB, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-454CT | Anti-Human SIRPA Recombinant Antibody (AM4-1) | ELISA | Human antibody |
| TAB-454CT-S(P) | Anti-Human SIRPA Recombinant Antibody scFv Fragment (AM4-1) | ELISA | Human antibody |
| TAB-454CT-F(E) | Anti-Human SIRPA Recombinant Antibody Fab Fragment (AM4-1) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1381CT | Recombinant Mouse anti-Rat SIRPA Monoclonal antibody (FE0) | FC, IHC-Fr, IP, WB | |
| HPAB-0023-LSX | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-1) | ELISA, Inhib | Humanized IgG |
| HPAB-0024-LSX | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-4) | ELISA | Humanized IgG |
| HPAB-0025-LSX | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-5) | ELISA, Inhib | Humanized IgG |
| PABJ-0078 | Human Anti-SIRPA Recombinant Antibody (PABJ-0078) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0465MZ | Chicken Anti-PTPNS1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1970CQ | Recombinant Rat Anti-Sirpa Antibody (P84) | FC, BL, IF, IHC, IP | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1971CQ | Recombinant Mouse Anti-Sirpa Antibody (CBL650) | WB, FC, CyTOF, Neut | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4429 | Hi-Affi™ Recombinant Rabbit Anti-SIRPA Monoclonal Antibody (SI522DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0023-LSX-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-1); scFv Fragment | ELISA | Humanized scFv |
| HPAB-2559LY-S(P) | Human Anti-SIRPA Recombinant Antibody; scFv Fragment (HPAB-2559LY-S(P)) | Inhib | Human scFv |
| PABJ-0078-S(P) | Human Anti-SIRPA Recombinant Antibody scFv Fragment (PABJ-0078-S(P)) | ELISA | Human scFv |
| PABJ-0084-S(P) | Human Anti-SIRPA Recombinant Antibody scFv Fragment (PABJ-0084-S(P)) | ELISA, Block | Human scFv |
| PABJ-0085-S(P) | Human Anti-SIRPA Recombinant Antibody scFv Fragment (PABJ-0085-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-080CN | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35) | ELISA, Inhib, FuncS | Human IgG |
| NS-080CN-F(E) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35); Fab Fragment | ELISA | Human Fab |
| NS-080CN-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0386-YC-F(E) | Human Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-N0386-YC-F(E)) | ELISA, FC | Human Fab |
| HPAB-N0387-YC-F(E) | Mouse Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-N0387-YC-F(E)) | ELISA, FC | Mouse Fab |
| PABJ-0078-F(E) | Human Anti-SIRPA Recombinant Antibody Fab Fragment (PABJ-0078-F(E)) | ELISA | Human Fab |
| PABJ-0084-F(E) | Human Anti-SIRPA Recombinant Antibody Fab Fragment (PABJ-0084-F(E)) | ELISA, Block | Human Fab |
| PABJ-0085-F(E) | Human Anti-SIRPA Recombinant Antibody Fab Fragment (PABJ-0085-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY86 | Human Anti-SIRPA (clone 29-AM3-35) scFv-Fc Chimera | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC143 | Recombinant Anti-SIRPA Vesicular Antibody, EV Displayed (VS-0425-YC143) | Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6598 | Anti-SIRPA Immunohistochemistry Kit | IHC | |
| VS-0525-XY6599 | Anti-Mouse SIRPA Immunohistochemistry Kit | IHC | |
| VS-0525-XY6600 | Anti-Rat SIRPA Immunohistochemistry Kit | IHC |
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