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    Recombinant Anti-CD28 Vesicular Antibody, EV Displayed (VS-0425-YC69)

    CAT#: VS-0425-YC69

    The Recombinant Anti-CD28 Vesicular Antibody, EV Displayed (VS-0425-YC69) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD28-expressed cells or tissues. The CD28 is a protein involved in immune response pathways, linked with conditions like Mycosis Fungoides.

    Gene Expression
    ❮
    Figure 1 Lymph node Figure 2 Tonsil Figure 3 RNA cell line category: Group enriched (Karpas-707, RPMI-8226, U-266/70, U-266/84)
    ❯

    Recombinant Antibody

    • Application
    • ELISA, FC, Neut, Cell-uptake
    • Product Type
    • Ab-Fc-EVs
    • Antibody Quantification (Ab/EV)
    • ~100 Ab/EV
    • Target
    • CD28
    • Host Animal
    • Human
    • Antibody Isotype
    • IgG
    • Species Reactivity
    • Human
    • Expression Cell
    • Mammalian cell

    Engineered EVs

    • EV-sorting domain
    • CD63
    • Fc-binding domain
    • z domain
    • EV Size
    • 30~150 nm
    • Producing Cell
    • HEK293F
    • Isolation Method
    • Gradient centrifugation
    • Purification
    • qEV size exclusion chromatography
    • Binding Affinity
    • Kd = 0.85 µg/mL
    • Concentration
    • 1 x 10¹⁰
    • Size
    • 1 mL
    • Buffer
    • PBS
    • Storage
    • Store at -80°C for 12 months

    Target

    • Full Name
    • CD28 molecule
    • Cellular Localization
    • Plasma membrane
    • Introduction
    • CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Th2 Differentiation Pathway and RET signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.
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    Related Diseases

    Rheumatoid Arthritis Rheumatoid Arthritis
    Systemic Lupus Erythematosus Systemic Lupus Erythematosus
    Allograft Rejection Allograft Rejection
    Autoimmune Thyroid Disease Autoimmune Thyroid Disease
    Graft-versus-Host Disease Graft-versus-Host Disease
    Maturity Onset Diabetes of the Young Maturity Onset Diabetes of the Young

    Downloadable Resources

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    Datasheet

    Datasheet - VS-0425-YC69.pdf

    MSDS

    MSDS - VS-0425-YC69.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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