HuTN228 is a recombinant monoclonal antibody targeting CD28. It is a humanized antibody with potential applications in transplant rejection treatment. HuTN228 antibodies specifically recognize the CD28 antigen through interactions in the V-region. The IC50 value of HuTN228 is 0.5 g/ml.
Figure 1 The binding of FITC-labeled MuTN228 to P815/CD28′ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in a flow cytometry competition experiment.
Figure 2 ELISA competition assay.
The binding of biotinylated MuTN228 to sCD28-Fc in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in an ELISA competition experiment.
Figure 3 I¹²⁵ competition assay. The binding of ¹²⁵I labeled MuTN228 to P815/CD28+ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in an ¹²⁵I labeled antibody competition experiment.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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HPAB-0132CQ-S(P) | Human Anti-CD28 Recombinant Antibody (clone FR255734); scFv Fragment | ELISA, IHC, Block | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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