Human Anti-CD28 Recombinant Antibody (clone FR255734); scFv Fragment (CAT#: HPAB-0132CQ-S(P))

This product is a recombinant human antibody scFv fragment that recognizes CD28. FR255734 is a humanized IgG2κ anti-human CD28 antibody that has the complementary determining regions of the mouse anti-human monoclonal antibody TN228 and the Fc domain of human IgG2M3 in which two amino acid mutations (V234A, G237A) have been introduced into the human γ2 chain to eliminate binding of the antibody to FcγR. FR255734 does not cross-react with mouse CD28.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Human CD28-transfected mouse fibroblast L cells, and fusing immune splenocytes with P3 U1 myeloma cells
  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Human scFv
  • Specificity
  • Human CD28
  • Species Reactivity
  • Human
  • Clone
  • FR255734
  • Applications
  • ELISA, IHC, Block
  • Related Disease
  • Psoriasis

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD28 Molecule; CD28 Antigen; Tp44; T-Cell-Specific Surface Glycoprotein CD28; T-Cell-Specific Surface Glycoprotein; CD28 Antigen (Tp44);

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone FR255734"

See other products for "CD28"

Chimeric Antibody

CAT Product Name Application Type
TAB-068LC Anti-Human CD28 Recombinant Antibody (ChTN228) ELISA, FC Chimeric antibody (mouse/human)
TAB-068LC-S(P) Anti-Human CD28 Recombinant Antibody scFv Fragment (ChTN228) FC, ELISA Chimeric antibody (mouse/human)
TAB-068LC-F(E) Anti-Human CD28 Recombinant Antibody Fab Fragment (ChTN228) FC, ELISA Chimeric antibody (mouse/human)

Mouse Antibody

CAT Product Name Application Type
PABX-031 Recombinant Mouse Anti-CD28 Antibody (5.11A1) WB, ELISA, FuncS, Activ IgG
PABX-031-F (E) Recombinant Mouse Anti-CD28 Antibody Fab Fragment (5.11A1) WB, ELISA, FuncS Fab

Human Antibody

CAT Product Name Application Type
PABX-031-S (P) Recombinant Mouse Anti-CD28 Antibody scFv Fragment (5.11A1) WB, ELISA, FuncS scFv

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-335CQ Hamster Anti-CD28 Recombinant Antibody (clone 37.51) IHC-Fr, FC, IP, Block, FuncS Hamster IgG
NEUT-336CQ Mouse Anti-CD28 Recombinant Antibody (clone E18) FC, Costim, Block Mouse IgG2b, κ

Rabbit Monoclonal Antibody

Recombinant Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H47 Afuco™ Anti-CD28 ADCC Recombinant Antibody (Lumretuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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