Recombinant Rabbit Anti-NRGN Detection Antibody (clone R55-1L-5)

CAT#: VS3-WK1885

This antibody is a rabbit recombinant antibody against human NRGN. It was developed by immunization of rabbit with recombinant human NRGN protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R18-3A-4 and R55-1L-5 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R55-1L-5 can be used in ELISA analysis to identify human NRGN.

Specifications

  • Immunogen
  • Recombinant human NRGN protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human NRGN
  • Species Reactivity
  • Human
  • Clone
  • R55-1L-5
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 0.01M PBS, pH 7.2
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Neurogranin; Neurogranin (Protein Kinase C Substrate, RC3); RC3; Calmodulin-Binding Protein; Protein Kinase C Substrate; Hng; Ng
  • Long Name
  • Neurogranin
  • Sequence Similarities
  • Belongs to the neurogranin family.
  • Cellular Localization
  • Cytosol
  • Post Translation Modifications
  • Phosphorylated at Ser-36 by PHK and PKC, phosphorylation prevents interaction with Calmodulin and interrupts several learning- and memory-associated functions.
  • Function
  • Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
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(Creative Biolabs Cat# VS3-WK1885, RRID: AB_3714415)

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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