Recombinant Rabbit Anti-NRGN Capture Antibody (clone R12-8Y-5) (CAT#: VS3-WK1898)
This antibody is a rabbit recombinant antibody against human NRGN. It was developed by immunization of rabbit with recombinant human NRGN protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R12-8Y-5 and R35-2F-4. The clone R12-8Y-5 can be used as a capture antibody in ELISA analysis to identify human NRGN.
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Specifications
- Immunogen
- Recombinant human NRGN protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NRGN
- Species Reactivity
- Human
- Clone
- R12-8Y-5
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Neurogranin; Neurogranin (Protein Kinase C Substrate, RC3); RC3; Calmodulin-Binding Protein; Protein Kinase C Substrate; Hng; Ng
- Gene ID
- 4900
- UniProt ID
- Q92686
- Long Name
- Neurogranin
- Sequence Similarities
- Belongs to the neurogranin family.
- Cellular Localization
- Cytosol
- Post Translation Modifications
- Phosphorylated at Ser-36 by PHK and PKC, phosphorylation prevents interaction with Calmodulin and interrupts several learning- and memory-associated functions.
- Protein Refseq
- NP_001119653.1
- Function
- Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
Recommended Products
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1799 | Rabbit Anti-NRGN Recombinant Antibody (clone R08-8K7) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| VS3-WK1884 | Recombinant Rabbit Anti-NRGN Capture Antibody (clone R18-3A-4) | ELISA | Rabbit IgG |
| VS3-WK1885 | Recombinant Rabbit Anti-NRGN Detection Antibody (clone R55-1L-5) | ELISA | Rabbit IgG |
| VS3-WK1899 | Recombinant Rabbit Anti-NRGN Detection Antibody (clone R35-2F-4) | ELISA | Rabbit IgG |
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