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For Research Use Only. Not For Clinical Use.
Enzymes, Metabolic proteins, Plasma proteins
Intracellular, Membrane (different isoforms)
Cell type enhanced (Cardiomyocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Microglial cells, Excitatory neurons)
Low immune cell specificity
Cell line enhanced (ASC TERT1)
CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other (PubMed:14722083). Interacts with RRAD and CACNB2 (By similarity).
Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase