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COL3A1
Anti-COL3A1 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: ELISA, WB
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- Rabbit Anti-COL3A1 Recombinant Antibody (VS3-FY2672) (VS3-FY2672)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Mouse Anti-COL3A1 Recombinant Antibody (clone 4E5F4A11); scFv Fragment (HPAB-0910-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-COL3A1 Recombinant Antibody (clone 4E5F4A11); Fab Fragment (HPAB-0910-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Fibroblasts, Smooth muscle cells, Theca cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, ASC diff, ASC TERT1, fHDF/TERT166, HHSteC, HSkMC)
Interaction
Trimers of identical alpha 1(III) chains. The chains are linked to each other by interchain disulfide bonds. Trimers are also cross-linked via hydroxylysines. Interacts with ADGRG1 (PubMed:28258187).
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