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EGFR & CD3

Anti-EGFR & CD3 Products
- Mouse Anti-NHP CD3 Recombinant Antibody (clone SK7) (VS-1024-XY89)
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- Species Reactivity: Human, Non-human primate
- Type: Mouse IgG1, kappa
- Application: IHC, FC
- Human Anti-EGFR Recombinant Antibody (clone EGL6) (HPAB-AP641-YC)
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- Derivation: Human Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF, Inhib
- Human Anti-EGFR Recombinant Antibody (clone EGL5) (HPAB-AP640-YC)
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- Derivation: Human Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF, Inhib
- Human Anti-EGFR Recombinant Antibody (clone EGL4) (HPAB-AP639-YC)
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- Derivation: Human Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF, Inhib
- Human Anti-EGFR Recombinant Antibody (clone EGL3) (HPAB-AP638-YC)
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- Derivation: Human Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF, Inhib
- Human Anti-EGFR Recombinant Antibody (clone EGL2) (HPAB-AP637-YC)
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- Derivation: Human Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF, Inhib
- Human Anti-EGFR Recombinant Antibody (HPAB-1519-FY) (HPAB-1519-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody (clone 11B2) (HPAB-0358-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC
- Human Anti-EGFR Recombinant Antibody (HPAB-0422-FY) (HPAB-0422-FY)
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- Species Reactivity: Human
- Type: Human IgG2
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody (HPAB-0421-FY) (HPAB-0421-FY)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody (HPAB-0420-FY) (HPAB-0420-FY)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: Inhib
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Human Anti-EGFR Recombinant Antibody (HPAB-0419-FY) (HPAB-0419-FY)
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) IgG1
- Application: Cyt, ELISA, FC
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Human Anti-EGFR Recombinant Antibody (HPAB-0424-FY) (HPAB-0424-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: IF
- Rat Anti-CD3 Antibody (clone Dow2), mRNA (TAB-0365CL-mRNA)
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- Species Reactivity: Mouse
- Human Anti-CD3 Antibody (clone hc3E3), mRNA (HPAB-0442-YJ-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD3 Antibody (clone m3E3), mRNA (HPAB-0441-YJ-mRNA)
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- Species Reactivity: Human
- Human Anti-CD3 Antibody, mRNA (TAB-0417CL-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD3 Antibody (clone G3(3)), mRNA (FAMAB-0053YC-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD3 Antibody (clone FN18), mRNA (FAMAB-0044CQ-mRNA)
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- Species Reactivity: Rhesus
- Human Anti-CD3 Agonistic Antibody (VS-0724-XY16) (VS-0724-XY16)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Agonistic assays
- Human Anti-EGFR Recombinant Antibody (HPAB-0423-FY) (HPAB-0423-FY)
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- Species Reactivity: Human
- Type: Human IgG2
- Application: Agonist
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V2) (HPAB-0895-WJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V1) (HPAB-0894-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IF, ELISA
- Human Anti-CD3 Recombinant Antibody (clone h1D10) (HPAB-1527WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FC
- Mouse Anti-CD3 Recombinant Antibody (clone 1D10) (HPAB-1526WJ)
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Human Anti-EGFR Recombinant Antibody (clone CBL155) (HPAB-3392LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody (clone CBL154) (HPAB-3391LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody (clone CBL141) (HPAB-2822LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3) (HPAB-0441-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (clone hc3E3) (HPAB-0442-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone N6-3) (HPAB-0357-YJ)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FuncS
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007) (HPAB-1181WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody (clone N5-4) (HPAB-0356-YJ)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FuncS
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007); scFv Fragment (HPAB-1181WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (clone hc3E3); scFv Fragment (HPAB-0442-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone CBL155); scFv Fragment (HPAB-3392LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3); scFv Fragment (HPAB-0441-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone CBL154); scFv Fragment (HPAB-3391LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody (clone CBL141); scFv Fragment (HPAB-2822LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone 3524); scFv Fragment (HPAB-1126-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (clone h1D10) (HPAB-1527WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FC
- Mouse Anti-EGFR Recombinant Antibody (clone 11B2); scFv Fragment (HPAB-0358-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IHC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (clone 1D10) (HPAB-1526WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Human Anti-EGFR Recombinant Antibody (clone N6-3); scFv Fragment (HPAB-0357-YJ-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FuncS
- Human Anti-EGFR Recombinant Antibody (clone N5-4); scFv Fragment (HPAB-0356-YJ-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FuncS
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V2); scFv Fragment (HPAB-0895-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V1); scFv Fragment (HPAB-0894-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0424-FY-S(P)) (HPAB-0424-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: IF
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0423-FY-S(P)) (HPAB-0423-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Agonist
- Human Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0422-FY-S(P)) (HPAB-0422-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody scFv Fragment (HPAB-0421-FY-S(P)) (HPAB-0421-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody scFv Fragment (HPAB-0420-FY-S(P)) (HPAB-0420-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0419-FY-S(P)) (HPAB-0419-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Cyt, ELISA, FC
- Human Anti-EGFR Recombinant Antibody Fab Fragment (HPAB-1519-FY-F(E)) (HPAB-1519-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody scFv Fragment (HPAB-1519-FY-S(P)) (HPAB-1519-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-0424-FY-F(E)) (HPAB-0424-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: IF
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-0423-FY-F(E)) (HPAB-0423-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Agonist
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-0422-FY-F(E)) (HPAB-0422-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody Fab Fragment (HPAB-0421-FY-F(E)) (HPAB-0421-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody Fab Fragment (HPAB-0420-FY-F(E)) (HPAB-0420-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-0419-FY-F(E)) (HPAB-0419-FY-F(E))
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) Fab
- Application: Cyt, ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V2); Fab Fragment (HPAB-0895-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
- Human Anti-EGFR Recombinant Antibody (clone YZ-EGFR V1); Fab Fragment (HPAB-0894-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
- Mouse Anti-EGFR Recombinant Antibody (clone 11B2); Fab Fragment (HPAB-0358-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, IHC
- Human Anti-EGFR Recombinant Antibody (clone N6-3); Fab Fragment (HPAB-0357-YJ-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FuncS
- Human Anti-EGFR Recombinant Antibody (clone N5-4); Fab Fragment (HPAB-0356-YJ-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FuncS
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (clone 1D10) (HPAB-1526WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (clone h1D10) (HPAB-1527WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FC
- Human Anti-EGFR Recombinant Antibody (clone 3524); Fab Fragment (HPAB-1126-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone 2224); Fab Fragment (HPAB-1125-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone P2/4); Fab Fragment (HPAB-1124-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone P2/2); Fab Fragment (HPAB-1123-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone P2/1); Fab Fragment (HPAB-1122-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007); Fab Fragment (HPAB-1181WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone hc3E3); Fab Fragment (HPAB-0442-YJ-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone CBL154); Fab Fragment (HPAB-3391LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3); Fab Fragment (HPAB-0441-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (clone CBL141); Fab Fragment (HPAB-2822LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-EGFR Recombinant Antibody (clone CBL155); Fab Fragment (HPAB-3392LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
- Recombinant Camelid Anti-CD3 Single Domain Antibody (HPAB-1029WJ)
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, IP, FuncS
- Anti-CD3 Immunohistochemistry Kit (VS-0325-XY360)
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- Species Reactivity: Human
- Target: CD3
- Application: IHC
- Human Anti-CD3 (clone YTH 12.5) scFv-Fc Chimera (VS-0125-FY56)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ELISA, FC
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- Targets: EGFR & CD3
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ICC
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- Antibody Host: Mouse
- Antibody Reactivity: Human
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.