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ELK1

Anti-ELK1 Products
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IP
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Rabbit Anti-ELK1 Recombinant Antibody (clone CBACN-212) (MRO-0530-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, IP, ChIP
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- Species Reactivity: Human
- Application: ELISA, WB
- AbPlus™ Anti-ELK1 Magnetic Beads (VS-0724-YC160) (VS-0724-YC160)
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- Target: ELK1
- Target Species: Human
- Application: IP, Protein Purification
- Anti-ELK1 Immunohistochemistry Kit (VS-0525-XY2251)
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- Species Reactivity: Human
- Target: ELK1
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC-P, IP, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-p, IF, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]
Protein class
RAS pathway related proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Granulosa cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts in its sumoylated form with PIAS2/PIASX which enhances its transcriptional activator activity (PubMed:15920481). Interacts with MAD2L2; the interaction is direct and promotes phosphorylation by the kinases MAPK8 and/or MAPK9 (PubMed:17296730). Interacts with POU1F1 (PubMed:26612202).
Molecular function
Activator, DNA-binding
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