


MSH2

Anti-MSH2 Products
- Recombinant Mouse Anti-MSH2 Monoclonal Antibody (10G1) (MRO-1026-CN)
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- Species Reactivity: Human, Rat
- Type: Mouse IgG2b
- Application: WB, IHC
- Recombinant Mouse Anti-MSH2 Monoclonal Antibody (10G2) (MRO-1027-CN)
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- Species Reactivity: Human, Rat
- Type: Mouse IgG2b
- Application: WB, IHC
- Recombinant Mouse Anti-MSH2 Monoclonal Antibody (10G3) (MRO-1028-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2b
- Application: WB, IHC
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: ELISA, WB, IHC
- AbPlus™ Anti-MSH2 Magnetic Beads (VS-0724-YC845) (VS-0724-YC845)
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- Target: MSH2
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
- Mouse Anti-MSH2 Recombinant Antibody (VS3-CJ961) (VS3-CJ961)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC
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- Type: Mouse IgG1
- Application: ELISA, WB, ICC, FC
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- Type: Mouse IgG1
- Application: ELISA, ICC, WB, FC, IHC
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- Type: Mouse IgG2a
- Application: ELISA, WB, IHC, FC
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- Type: Mouse IgG1
- Application: ELISA, ICC, FC
- Rabbit Anti-MSH2 Polyclonal Antibody (MRO-2044-CN) (MRO-2044-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, FC
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- Species Reactivity: Human, Monkey
- Type: Mouse IgG
- Application: WB, IHC, IF, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-Fr, IHC-P, WB, IP, IF
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- Species Reactivity: human
- Type: Rabbit IgG
- Application: IHC-P
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-Fr, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC/IF, IHC-P, WB
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- Antibody Host: Mouse
- Antibody Reactivity: Human
- Anti-MSH2 Immunohistochemistry Kit (VS-0325-XY1375)
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- Species Reactivity: Human, Mouse
- Target: MSH2
- Application: IHC
- Mouse Anti-MSH2 Recombinant Antibody (clone 4F10D6) (VS7-0425-WR417)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC
- Mouse Anti-MSH2 Monoclonal Antibody (clone 1B3A8A8) (VS7-0425-WR418)
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- Species Reactivity: Human, Monkey
- Type: Mouse IgG1
- Application: WB, IHC, ICC
- Mouse Anti-MSH2 Monoclonal Antibody (VS7-0425-WR419) (VS7-0425-WR419)
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- Species Reactivity: Human, Monkey
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, ELISA
- Anti-Mouse MSH2 Immunohistochemistry Kit (VS-0525-XY4516)
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- Species Reactivity: Human, Mouse, Rat
- Target: MSH2
- Application: IHC
- Anti-Human MSH2 Immunohistochemistry Kit (VS-0525-XY4517)
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- Species Reactivity: Human, Monkey, Monkey
- Target: MSH2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Component of the DNA mismatch repair (MMR) complex composed at least of MSH2, MSH3, MSH6, PMS1 and MLH1 (PubMed:26300262). Heterodimer consisting of MSH2-MSH6 (MutS alpha) or MSH2-MSH3 (MutS beta) (PubMed:8942985). Both heterodimers form a ternary complex with MutL alpha (MLH1-PMS1) (PubMed:9788596, PubMed:10856833, PubMed:11427529, PubMed:11429708, PubMed:12414623, PubMed:14676842). Interacts with MCM9; the interaction recruits MCM9 to chromatin (PubMed:26300262). Interacts with MCM8 (PubMed:26300262). Interacts with EXO1 (PubMed:9788596, PubMed:10856833, PubMed:11427529, PubMed:11429708, PubMed:12414623, PubMed:14676842). Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex (PubMed:10783165). This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains (PubMed:10783165). Interacts with ATR (PubMed:14657349). Interacts with SLX4/BTBD12; this interaction is direct and links MutS beta to SLX4, a subunit of different structure-specific endonucleases (PubMed:19596235). Interacts with SMARCAD1 (PubMed:18675275).
DNA-binding