Anti-Human CD28 Recombinant Antibody scFv Fragment (TGN1412) (CAT#: TAB-064LC-S(P))

TAB-064LC is a superagonistic monoclonal antibody (mAb) capable of fully activating T-cells by cross-linking CD28 molecules, even without signal 1, which sets it apart from conventional anti-CD28 mAbs. TAB-064LC exhibits a binding affinity to human CD28, with an EC50 value of 4.4 nM. TAB-064LC exhibits a binding affinity to human T cells, with EC50 values measured at 2.5 nM. TAB-064LC-S(P) antibody is the scfv fragment antibody form of TAB-064LC antibody. Single-chain variable fragments (scFvs) are artificial constructs consisting of the variable regions of the immunoglobulin heavy and light chains connected by a peptide linker.

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  • Gene Expression
  • Datasheet
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  • COA
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • TGN1412
  • Applications
  • FC
  • Related Disease
  • Inflammatory diseases, Autoimmune diseases

Target

  • Alternative Names
  • Tp44; CD28

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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