Anti-DENV antibody is a Mouse antibody of IgG2a κ class that binds to an DENV. This antibody recognize dengue virus, serotype 1 envelope protein.
Figure 1 Expression of DV1 EDIII and EDIII-ectoM by recombinant MV vector.
(B) Detection of DV1 EDIII in Vero cells infected for 24h with MV-EDIII or MV-EDIII-ectoM. EDIII was detected in two different experiments using either anti-EDIII 4E11 antibody (red label) or anti-DV1-HMAF (green label).
Brandler, S., Lucas-Hourani, M., Moris, A., Frenkiel, M. P., Combredet, C., Février, M., ... & Tangy, F. (2007). Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus. PLoS neglected tropical diseases, 1(3), e96.
Figure 2 Expression of DV1 EDIII and EDIII-ectoM by recombinant MV vector.
(D) Western blot analysis of recombinant rEDIII protein produced in E.coli (100 ng) and recombinant rEDIII or rEDIII-ectoM proteins produced in drosophila S2 cells supernatants (0.5, 1 and 2 µg/well). DV1 EDIII was probed with 4E11 mouse monoclonal anti-DV1 EDIII.
Brandler, S., Lucas-Hourani, M., Moris, A., Frenkiel, M. P., Combredet, C., Février, M., ... & Tangy, F. (2007). Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus. PLoS neglected tropical diseases, 1(3), e96.
Figure 3 Biochemical characterization of rsDIIIs indicating abolishment of unfavorable epitopes.
(B) RsDIIIs bind only to MAb 4E11 with high affinity and show little or no binding to MAbs 2H12 and 3H5 by ELISA. In contrast, WT DENV-2 EDIII binds to all three antibodies. The data are graphed as means ± SD from the results of two experiments performed in triplicate. Abs., absorbance.
Frei, J. C., Wirchnianski, A. S., Govero, J., Vergnolle, O., Dowd, K. A., Pierson, T. C., ... & Lai, J. R. (2018). Engineered dengue virus domain III proteins elicit cross-neutralizing antibody responses in mice. Journal of virology, 92(18), e01023-18.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-275 | Recombinant Anti-DENV E-DIII Antibody | ELISA, WB, FC, FuncS | IgG |
MHH-275 | Recombinant Human Anti-DENV E-DIII Antibody | ELISA, WB, FC, FuncS | IgG |
PABC-031 | Recombinant Mouse Anti-DENV E-DIII Antibody (1A1D-2) | WB, ELISA | IgG |
PABL-437 | Recombinant Mouse Anti-DENV EDIII Antibody (2H12) | ELISA, Neut | IgG |
MRO-1612CQ | Recombinant Human Anti-DENV E-DIII Antibody (DV10) | ELISA, Neut | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-275-F(E) | Recombinant Anti-DENV E-DIII Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
MHH-275-F(E) | Recombinant Human Anti-DENV E-DIII Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
PFBC-031 | Recombinant Mouse Anti-DENV E-DIII Antibody Fab Fragment (1A1D-2) | WB, ELISA | IgG |
PFBL-434 | Recombinant Mouse Anti-DENV EDIII Antibody Fab Fragment (2H12) | ELISA, Neut | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-275-S(P) | Recombinant Anti-DENV E-DIII Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
MHH-275-S(P) | Recombinant Human Anti-DENV E-DIII Antibody scFv Fragment | Neut, IF, FuncS | scFv |
PSBC-031 | Recombinant Mouse Anti-DENV E-DIII Antibody scFv Fragment (1A1D-2) | WB, ELISA | scFv |
PSBL-434 | Recombinant Mouse Anti-DENV EDIII Antibody scFv Fragment (2H12) | ELISA, Neut | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-044 | Recombinant Mouse Anti-DENV Antibody (3E31) | WB, ELISA, FuncS, Neut, Inhibt | IgG |
PABX-054 | Recombinant Mouse Anti-DENV Antibody (E111) | WB, ELISA, FuncS, SPR, Neut | IgG |
PABX-044-S (P) | Recombinant Mouse Anti-DENV Antibody scFv Fragment (3E31) | WB, ELISA, FuncS | scFv |
PABX-044-F (E) | Recombinant Mouse Anti-DENV Antibody Fab Fragment (3E31) | WB, ELISA, FuncS | Fab |
PABX-054-F (E) | Recombinant Mouse Anti-DENV Antibody Fab Fragment (E111) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-054-S (P) | Recombinant Mouse Anti-DENV Antibody scFv Fragment (E111) | WB, ELISA, FuncS | scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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