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    Mouse Anti-LRP6 Recombinant Antibody scFv Fragment (TAB-0107CL-S(P)) (CAT#: TAB-0107CL-S(P))

    Anti-LRP6 antibodies can bind LRP6 epitopes with high affinity and then enhance Wnt signaling and/or antagonize Dkk1 activity which is related with the treatment of a variety of diseases, such as bone diseases, wound healing and gastrointestinal diseases.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IHC staining of human colon
    Figure 1 IHC staining of human colon
    (Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/ihc_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human kidney
    Figure 2 IHC staining of human kidney
    (High expression. RNA expression: 4.4 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/29925/ihc_selected.jpg
    Figure 3 IHC staining of human lymph node
    Figure 3 IHC staining of human lymph node
    (Low expression. RNA expression: 0.8 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/29925/62204_A_7_8_val_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12171_B_8_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12026_A_8_4.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Spermatogonia cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12026_A_4_6.jpg
    RNA Expression
    Figure 7 RNA cell line category: Low cell line specificity
    Figure 7 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000070018-LRP6

    Specifications

    • Immunogen
    • Extracellular domain of LRP6
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Species Reactivity
    • Cross-react with mouse LRP6
    • Related Disease
    • Osteoporosis, rheumatoid arthritis, osteolytic lesions caused by osteoarthritis and multiple myeloma, gas-trointestinal disease and wound healing, radiation- or chemotherapy-induced mucositis

    Target

    • Alternative Names
    • LRP6; low density lipoprotein receptor-related protein 6; ADCAD2; low-density lipoprotein receptor-related protein 6; LRP-6

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "LRP6"

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    IgG Antibody Products Mouse Antibody Products Chimeric Antibody Products Humanized Antibody Products Human Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Single Domain Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-2487z Mouse Anti-LRP6 Recombinant Antibody (clone 25B10) WB, ELISA, IF, IHC, IP Mouse IgG2a, κ
    PABC-205 Mouse Anti-LRP6 Recombinant Antibody (PABC-205) FC, WB, FuncS, IF, Inhib Mouse IgG
    HPAB-0007-FY Human Anti-LRP6 Recombinant Antibody (HPAB-0007-FY) ELISA Human IgG1, λ
    HPAB-0012-FY Human Anti-LRP6 Recombinant Antibody (HPAB-0012-FY) Cyt, WB, Stim, Inhib, Activ, Block, IP, ELISA Human IgG
    VS3-WK2089 Rabbit Anti-LRP6 (pS1490) Recombinant Antibody (clone R76-2O-7) WB Rabbit IgG

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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