Human Anti-EGFR Recombinant Antibody (clone MR1); Fab Fragment (CAT#: PFBC-040)
Recombinant Human Antibody (MR1) Fab Fragment is specific to EGFRvIII dodecapeptide (EEKKGNYVVTDH), expressed in Chinese Hamster Ovary cells (CHO).
Specific Inquiry
Figure 1 Cells were allowed to adhere and culture for 48 h before the addition of either 3.2 µmol/L of antisense oligos and/or 2.5 nm of Taxol for a single 24-h treatment, which was then followed by 2 d of additional growth before the addition of WST-1.
Rubenstein, M., Slobodskoy, L., Mirochnik, Y., & Guinan, P. (2003). Inhibition of PC-3 prostate cancer cell growth in vitro using both antisense oligonucleotides and Taxol. Medical Oncology, 20(1), 29-35.
Figure 2 Cells were allowed to adhere and culture for 48 h before the addition of either 6.64 µmol/L of antisense oligos and/or 5 nm of Taxol for a single 24-h treatment, which was then followed by 2 d of additional growth before the addition of WST-1.
Rubenstein, M., Slobodskoy, L., Mirochnik, Y., & Guinan, P. (2003). Inhibition of PC-3 prostate cancer cell growth in vitro using both antisense oligonucleotides and Taxol. Medical Oncology, 20(1), 29-35.
Specifications
- Immunogen
- Human epidermal growth factor receptor
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human EGFR
- Species Reactivity
- Human
- Clone
- MR1
- Applications
- Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody Fab fragment MR1 has been reported in application of Blocking. It's recommended that the optimal antibody concentration, dilution, incubition time etc. are best to be carefully titrated in specific assays.
Target
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
- Gene ID
- 1956
- UniProt ID
- P00533
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
JAK-STAT Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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