Human Anti-CD4 Recombinant Antibody (clone Variant D); Fab Fragment

Name: Human Anti-CD4 Recombinant Antibody (clone Variant D); Fab Fragment
SKU: HPAB-0759-CN-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-0759-CN-F(E)

Variant D is a non-depleting IgG1 monoclonal antibody variant with amino acid substitutions N297A, N434H in the heavy chain to increase serum half life. This antibody can be used for treating autoimmune disorders in mammalian subjects.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4

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Specifications

Host Species
Human

Type
Human Fab

Specificity
Human

Species Reactivity
Human

Clone
Variant D

Applications
ELISA, FC

Related Disease
Autoimmune diseases

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut;

Gene ID
920

UniProt ID
P01730

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Related Diseases

Primary Immunodeficiency

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0759-CN-F(E).pdf

MSDS

MSDS - HPAB-0759-CN-F(E).pdf

COA

Certificate of Analysis Lookup

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