Rabbit Anti-FOXP1 Recombinant Antibody (VS3-FY2712) (CAT#: VS3-FY2712)
The anti-FOXP1 antibody is specifically engineered to target mouse FOXP1 protein. It shows capability of cross-reacting with rat. This monoclonal antibody proves valuable in disease research related to Intellectual Developmental Disorder With Language Impairment and with or without Autistic Features and Intellectual Disability-Severe Speech Delay-Mild Dysmorphism Syndrome.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/if_selected.jpg
Figure 3 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows moderate nuclear positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/11170_A_4_8_selected.jpg
(Immunohistochemical staining of human tonsil shows moderate nuclear positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/11170_A_4_8_selected.jpg
Figure 4 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong nuclear and cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/ihc_selected.jpg
(Immunohistochemical staining of human colon shows strong nuclear and cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/ihc_selected.jpg
Figure 5 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/617_H10_1_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/617_H10_1_red_green.jpg
Figure 6 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_B_8_5.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_B_8_5.jpg
Figure 7 Colon
(Endocrine cells
Staining:High
Intensity: Strong
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Fibroblasts
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_3.jpg
(Endocrine cells
Staining:High
Intensity: Strong
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Fibroblasts
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_3.jpg
Figure 8 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_8_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_8_5.jpg
Figure 9 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_4_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_4_6.jpg
Figure 10 Lymph node
(Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_8.jpg
(Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_8.jpg
Figure 11 RNA cell line category: Cell line enhanced .
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000114861-FOXP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000114861-FOXP1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Forkhead box P1 of mouse and rat origins
- Species Reactivity
- Mouse, Rat
- Applications
- WB, IHC, ICC, IP
- Conjugate
- Unconjugated, FITC
- Related Disease
- Intellectual Developmental Disorder With Language Impairment And With Or Without Autistic Features and Intellectual Disability-Severe Speech Delay-Mild Dysmorphism Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- Forkhead Box P1; Fork Head-Related Protein Like B; Mac-1-Regulated Forkhead; Glutamine-Rich Factor 1; MFH; PAX5/FOXP1 Fusion Protein
- Gene ID
- 27086
- UniProt ID
- Q9H334
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 10 sites, 2 O-linked glycans (10 sites)
- Protein Refseq
- NP_001012523.1; NP_001231737.1; NP_001231739.1; NP_001231741.1; NP_001231742.1
- Function
- Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2.
Essential transcriptional regulator of B-cell development.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-326 | Human Anti-FOXP1 Recombinant Antibody (clone T47) | IP, IF, ELISA | Human IgG |
| MOB-1070MZ | Recombinant Mouse Anti-Human FOXP1 Antibody | WB | Mouse antibody |
| VS3-XY725 | Mouse Anti-FOXP1 Recombinant Antibody (clone 6E4) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-XY726 | Mouse Anti-FOXP1 Recombinant Antibody (clone 6E4C4) | IHC, FC | Mouse IgG1 |
| VS13-YC422 | Rabbit Anti-FOXP1 Recombinant Antibody (VS13-YC422) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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