Rabbit Anti-FOXP1 Recombinant Antibody (VS3-FY2712)
CAT#: VS3-FY2712
The anti-FOXP1 antibody is specifically engineered to target mouse FOXP1 protein. It shows capability of cross-reacting with rat. This monoclonal antibody proves valuable in disease research related to Intellectual Developmental Disorder With Language Impairment and with or without Autistic Features and Intellectual Disability-Severe Speech Delay-Mild Dysmorphism Syndrome.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/if_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows moderate nuclear positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3876/11170_A_4_8_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human colon
Immunohistochemical staining of human colon shows strong nuclear and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 5 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/617_H10_1_red_green.jpg
Normal Tissue
Figure 6 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_B_8_5.jpg
Normal Tissue
Figure 7 Colon
Endocrine cells
Staining:High
Intensity: Strong
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Fibroblasts
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_3.jpg
Normal Tissue
Figure 8 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_8_5.jpg
Normal Tissue
Figure 9 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_4_6.jpg
Normal Tissue
Figure 10 Lymph node
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11501/27240_A_9_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced .
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000114861-FOXP1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Forkhead box P1 of mouse and rat origins
- Species Reactivity
- Mouse, Rat
- Applications
- WB, IHC, ICC, IP
- Conjugate
- Unconjugated, FITC
- Related Disease
- Intellectual Developmental Disorder With Language Impairment And With Or Without Autistic Features and Intellectual Disability-Severe Speech Delay-Mild Dysmorphism Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- Forkhead Box P1; Fork Head-Related Protein Like B; Mac-1-Regulated Forkhead; Glutamine-Rich Factor 1; MFH; PAX5/FOXP1 Fusion Protein
- Gene ID
- 27086
- UniProt ID
- Q9H334
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 10 sites, 2 O-linked glycans (10 sites)
- Protein Refseq
- NP_001012523.1; NP_001231737.1; NP_001231739.1; NP_001231741.1; NP_001231742.1
- Function
- Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2.
Essential transcriptional regulator of B-cell development.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "FOXP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-326 | Human Anti-FOXP1 Recombinant Antibody (clone T47) | IP, IF, ELISA | Human IgG |
| MOB-1070MZ | Recombinant Mouse Anti-Human FOXP1 Antibody | WB | Mouse antibody |
| MRO-0605-CN | Rabbit Anti-FOXP1 Recombinant Antibody (clone JF1017) | WB, IHC, FC | Rabbit IgG |
| VS3-XY725 | Mouse Anti-FOXP1 Recombinant Antibody (clone 6E4) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-XY726 | Mouse Anti-FOXP1 Recombinant Antibody (clone 6E4C4) | IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1347 | Hi-Affi™ Rabbit Anti-FOXP1 Recombinant Antibody (clone DS1347AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY116 | CytoStream™ Mouse Anti-FOXP1 Recombinant Antibody (clone JC12) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY861 | Anti-FOXP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2639 | Anti-Mouse FOXP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2638 | Anti-Human FOXP1 Immunohistochemistry Kit | IHC |
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