Human Anti-HIV-1 gp120 Recombinant Antibody (clone DRVIA7) (CAT#: MRO-3449CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. DRVIA7 specifically binds to gp120.


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ELISA

Figure 1 Interaction between DRVIA7 light chain and the N276 glycan determines the neutralizing breadth of the antibody.

Figure 1 Interaction between DRVIA7 light chain and the N276 glycan determines the neutralizing breadth of the antibody.

ELISA binding for DRVIA7 against YU2 gp120 (black) and T278G (i.e., no glycan at N276) YU2 gp120 (red), with the optical density (OD) plotted as a function of antibody dilution (μg/mL).

Kong, L., Ju, B., Chen, Y., He, L., Ren, L., Liu, J., ... & Shao, Y. (2016). Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity, 44(4), 939-950.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • DRVIA7
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone DRVIA7"

See other products for "HIV-1 gp120"

Single-domain Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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