Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced (CAT#: AFC-TAB-H05)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human IL13. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- IL13 (interleukin 13, IL-13) [Homo sapiens]
- Species Reactivity
- Human
- Clone
- Anrukinzumab
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Anrukinzumab
- Related Disease
- Ulcerative colitis (UC)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Anrukinzumab; 910649-32-0; IMA-638; IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;
- Gene ID
- 3596
- UniProt ID
- P35225
Related Resources
Please refer to Anrukinzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Anrukinzumab.
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "anrukinzumab"
Anti-Human IL13 Recombinant Antibody (Anrukinzumab)Recombinant Humanized (from mouse) antibody to Human IL13. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
See other products for "IL13"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1287z | Mouse Anti-IL13 Recombinant Antibody (clone 39B4) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| FN-189CQ | Rat Anti-Il13 Recombinant Antibody (clone CBL-1328) | FuncS, Neut, Block | Rat IgG1, κ |
| FN-190CQ | Rat Anti-Il13 Recombinant Antibody (clone CBL-1329) | ELISA, FuncS, FC | Rat IgG1, κ |
| HPAB-AP106-YC | Mouse Anti-IL13 Recombinant Antibody (HPAB-AP106-YC) | WB, ELISA, FC, IHC | Mouse IgG |
| HPAB-AP107-YC | Mouse Anti-IL13 Recombinant Antibody (HPAB-AP107-YC) | ELISA | Mouse IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218 | Anti-Human IL13 Recombinant Antibody (Tralokinumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - lambda |
| TAB-068ZJ | Anti-Human IL-13 Recombinant Antibody (01471/G6) | WB, ELISA, Neut | Human antibody |
| TAB-069ZJ | Human Anti-IL13 Recombinant Antibody (TAB-069ZJ) | ELISA, Neut, FC | Human IgG |
| TAB-070ZJ | Human Anti-IL13 Recombinant Antibody (TAB-070ZJ) | ELISA, Neut, FC | Human IgG |
| TAB-067ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (CNTO 607) | ELISA, Inhib | Human antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219 | Anti-Human IL13 Recombinant Antibody (Lebrikizumab) | ELISA, Neut, IF, IP, FC, FuncS | IgG4 - kappa |
| TAB-043ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (Lc6Hc2) | ELISA | Humanized antibody |
| TAB-044ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-044ZJ-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-045ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-045ZJ-S(P)) | ELISA, Block | Humanized scFv |
| TAB-046ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-046ZJ-S(P)) | ELISA, Block | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295); Fab Fragment | WB, IHC, FuncS | Human Fab |
| HPAB-0226CQ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-0226CQ-F(E)) | ELISA, Neut, FC, FuncS | Human Fab |
| HPAB-0227CQ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-0227CQ-F(E)) | ELISA, Neut, FC, FuncS | Human Fab |
| HPAB-0228CQ-F(E) | Mouse Anti-IL13 Recombinant Antibody (clone MJ2-7); Fab Fragment | ELISA, FC, Neut | Mouse Fab |
| HPAB-0229CQ-F(E) | Human Anti-IL13 Recombinant Antibody (clone huMJ2-7); Fab Fragment | ELISA, FC, Neut | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-598 | Mouse Anti-IL13 Recombinant Antibody (clone C836); scFv Fragment | Neut | Mouse scFv |
| HPAB-0286-YJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0286-YJ-S(P)) | ELISA, Antagonist, FuncS | Human scFv |
| HPAB-0287-YJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0287-YJ-S(P)) | ELISA, Neut, Inhib, FuncS | Mouse scFv |
| HPAB-0288-YJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0288-YJ-S(P)) | ELISA, Neut, Inhib, FuncS | Mouse scFv |
| HPAB-0289-YJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0289-YJ-S(P)) | ELISA, Neut, Inhib, FuncS | Humanized scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022ZJ | Anti-Human IL-13 Recombinant Antibody (C836) | ELISA | |
| TAB-022ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (C836) | ELISA | |
| TAB-023ZJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-023ZJ-S(P)) | ELISA, Block | Mouse scFv |
| TAB-022ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (C836) | ELISA | |
| TAB-023ZJ-F(E) | Mouse Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-023ZJ-F(E)) | ELISA, Block | Mouse Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-094ZJ | Anti-Human IL-13 Recombinant Antibody (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1171CQ | Mouse Anti-IL13 Recombinant Antibody (clone B-B13) | ELISA, ELISPOT, Neut | Mouse IgG1 |
| NEUT-1172CQ | Mouse Anti-IL13 Recombinant Antibody (clone 10X28) | Neut, WB | Mouse IgG1 |
| NEUT-1173CQ | Mouse Anti-IL13 Recombinant Antibody (clone 15H10) | Neut | Mouse IgG2b |
| NEUT-1188CQ | Mouse Anti-Il13 Recombinant Antibody (clone CBL611) | WB, Neut | Mouse IgG2b |
| NEUT-1189CQ | Rat Anti-Il13 Recombinant Antibody (clone 1316H) | FuncS, Neut | Rat IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1790 | Rabbit Anti-IL13 Recombinant Antibody (clone DS1790AB) | WB, ICC, FC, IP | Rabbit IgG |
| MOR-4610 | Rabbit Anti-IL13 Recombinant Antibody (clone TH123DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-017ML | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-219 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
| AFC-TAB-218 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-H05. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.