Afuco™ Anti-IL6R ADCC Recombinant Antibody (Sapelizumab), ADCC Enhanced (CAT#: AFC-TAB-691LC)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody Sapelizumab is a humanized monoclonal antibody that specifically binds to human IL-6R and can be potentially used in the treatment of inflammatory disease.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (THP-1, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
Figure 1 RNA cell line category: Cell line enhanced (THP-1, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Sapelizumab
- Applications
- ELISA
- Conjugate
- Unconjugated
- Related Disease
- Inflammatory disease
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1; interleukin-6 receptor subunit alpha; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha
- Gene ID
- 3570
- UniProt ID
- A0N0L5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL6R"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026 | Anti-Human IL6R Recombinant Antibody (Tocilizumab/Atlizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
| TAB-697LC-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-697LC-S(P)) | ELISA | Humanized scFv |
| TAB-691LC-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-691LC-F(E)) | ELISA | Humanized Fab |
| TAB-692LC-F(E) | Anti-human IL6R Fab Fragment (BOW070) | ELISA | Humanized antibody |
| TAB-696LC-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-696LC-F(E)) | ELISA | Humanized Fab |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L080E | IL6-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L080D | IL6-DT immunotoxin | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-245 | Human Anti-IL6R Recombinant Antibody (clone 6RL9) | WB, Neut, FuncS | Human IgG |
| HPAB-0016-YC | Human Anti-IL6R Recombinant Antibody (HPAB-0016-YC) | ELISA, Neut | Human IgG |
| HPAB-0165-YJ | Human Anti-IL6R Recombinant Antibody (HPAB-0165-YJ) | ELISA, Block, Inhib | Humanized IgG1, κ |
| HPAB-0446-WJ | Mouse Anti-IL6R Recombinant Antibody (HPAB-0446-WJ) | ELISA | Mouse IgG1 |
| HPAB-0447-WJ | Mouse Anti-IL6R Recombinant Antibody (HPAB-0447-WJ) | ELISA | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-245 | Human Anti-IL6R Recombinant Antibody (clone 6RL9); scFv Fragment | WB, Neut, FuncS | Human scFv |
| HPAB-0718-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0718-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0719-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0719-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0720-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0720-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0251CQ-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0251CQ-S(P)) | ELISA, FC, Block | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-245 | Human Anti-IL6R Recombinant Antibody (clone 6RL9); Fab Fragment | WB, Neut, FuncS | Human Fab |
| HPAB-0718-CN-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0718-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0719-CN-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0719-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0720-CN-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0720-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0251CQ-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0251CQ-F(E)) | ELISA, FC, Block | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-690LC-S(P) | Anti-human IL6R scFv Fragment (PM-1) | ELISA | |
| TAB-694LC-S(P) | Rabbit Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-694LC-S(P)) | ELISA | Rabbit scFv |
| TAB-690LC-F(E) | Anti-human IL6R Fab Fragment (PM-1) | ELISA | |
| TAB-694LC-F(E) | Rabbit Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-694LC-F(E)) | ELISA | Rabbit Fab |
| TAB-695LC-F(E) | Rabbit Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-695LC-F(E)) | ELISA | Rabbit Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1485CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL212) | FC, ELISA, Neut | Mouse IgG1, κ |
| NEUT-1486CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL261) | FC, Neut | Mouse IgG1 |
| NEUT-1487CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL279) | Neut, WB, ELISA, FC | Mouse IgG1 |
| NEUT-1489CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL425) | WB, FC, CyTOF, ELISA, Neut | Mouse IgG1 |
| NEUT-1491CQ | Mouse Anti-IL6R Recombinant Antibody (clone MM0409-6M30) | WB, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1488CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-F19) | Block | Mouse IgG1 |
| NEUT-1490CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-R6) | IHC-Fr, Inhib, FC, IP | Mouse IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-026 | Afuco™ Anti-IL6R ADCC Recombinant Antibody (Tocilizumab/Atlizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-032ML | Afuco™ Anti-IL6R ADCC Recombinant Antibody (Satralizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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