Mouse Anti-IRS1 Recombinant Antibody (clone IRS 8-63)
CAT#: FAMAB-1375CQ
This product is a recombinant mouse antibody that recognizes IRS1. The antibody was purified by affinity chromatography. It can be used in IB, IP, WB.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46433/824_C8_5_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5261/963_D12_1_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5261/19658_B_9_5.jpg
Normal Tissue
Figure 4 Cerebellum
Cells in granular layer Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5261/19658_B_9_8.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5261/19658_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5261/19658_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169047-IRS1
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Specifications
- Immunogen
- KLH conjugated rat IRS1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human and rodent IRS1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- IRS 8-63
- Applications
- IB, IP, WB
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Insulin Receptor Substrate 1
- UniProt ID
- P35570
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Related Signaling Pathways
Insulin Signaling Pathway
mTOR Signaling Pathway
PI3K-Akt Signaling Pathway
PPAR Signaling Pathway
Related Diseases
Insulin Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone IRS 8-63"
- CAT
- Product Name
See other products for "IRS1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2476z | Mouse Anti-IRS1 Recombinant Antibody (clone 36A2) | WB, FC, IHC | Mouse IgG2a |
| MRO-0874-CN | Recombinant Rabbit Anti-IRS1 Monoclonal Antibody (CBACN-326) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ905 | Rabbit Anti-IRS1 Recombinant Antibody (VS3-CJ905) | WB, ICC, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1540CQ | Recombinant Mouse Anti-IRS1 Antibody (CBL216) | Inhib | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1861 | Hi-Affi™ Recombinant Rabbit Anti-IRS1 Monoclonal Antibody (DS1861AB) | WB | IgG |
| MOR-4635 | Hi-Affi™ Recombinant Rabbit Anti-IRS1 Monoclonal Antibody (TH148DS) | WB, IHC-P | IgG |
| MOR-4689 | Hi-Affi™ Recombinant Rabbit Anti-IRS1 Monoclonal Antibody (TH203DS) | WB, IF, ICC, FC | IgG |
| MOR-0045-FY | Rabbit Anti-IRS1 Recombinant Antibody (clone AFY0016) | IHC, WB, Inhib | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4426 | PE-A*02:01/Human IRS1 (GLENGLNYI) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY286 | Mouse Anti-NHP IRS1 Recombinant Antibody (VS-1024-XY286) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3599 | Anti-IRS1 Immunohistochemistry Kit | IHC |
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