Rabbit Anti-MLANA Recombinant Antibody (clone R08-8B5) (CAT#: VS3-XY3428)
The rabbit recombinant antibody specifically recognizes MLANA (Melan-A), which plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL. It specifically reacts with human MLANA. It has been tested using Western Blot, Immunohistochemistry-Paraffin, Flow cytometry, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin, Flow cytometry and Immunofluorescence is 1/500-1/1000, 1/50-1/100, 1/50-1/100 and 1/50-1/200, respectively.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
Figure 3 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MLANA
- Species Reactivity
- Human
- Clone
- R08-8B5
- Applications
- WB, IHC-P, ICC, IF, FC
- Related Disease
- Melanoma In Congenital Melanocytic Nevus; Angiomyolipoma
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
FC: 1/50-1/100
Target
- Alternative Names
- MART1; MART-1
- Gene ID
- 2315
- UniProt ID
- Q16655
- Long Name
- Melan-A
- Cellular Localization
- Endoplasmic reticulum membrane, Golgi apparatus, Melanosome
- Post Translation Modifications
- Acylated. (Q16655-MAR1_HUMAN)
Modification sites at PhosphoSitePlus (Q16655)
Modification sites at neXtProt (NX_Q16655)
Glycosylation from GlyGen (Q16655) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_005502.1
- Function
- Involved in melanosome biogenesis by ensuring the stability of GPR143.
Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MLANA"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-096 | Recombinant Anti-human MLANA VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G050E | Anti-MLANA immunotoxin (Fab)-PE | Cytotoxicity assay, Function study |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0324MZ | Recombinant Mouse Anti-Human MLANA Antibody (clone B104) | IHC | Mouse antibody |
| MRO-0987-CN | Recombinant Rabbit Anti-MLANA Monoclonal Antibody (CBACN-366) | WB, IHC, FC | Rabbit IgG |
| MOB-0096F | Mouse Anti-MLANA Recombinant Antibody (MOB-0096F) | IHC-P, IF | Mouse IgG |
| VS3-XY1075 | Mouse Anti-MLANA Recombinant Antibody (clone 2F3B7) | ELISA, WB | Mouse IgG1 |
| VS3-XY1076 | Mouse Anti-MLANA Recombinant Antibody (clone 2F1) | ELISA, WB | Mouse IgG1 |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2240 | Hi-Affi™ Recombinant Rabbit Anti-MLANA Monoclonal Antibody (DS2240AB) | IHC-P, WB | IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-1008LC | Recombinant Mouse Anti-MLANA Antibody (Mab-1) | WB | IgG1 |
| EPAF-0579CQ | Recombinant Human Anti-Human MLANA Antibody (E6) | ELISA, FC | IgG |
| EPAF-0580CQ | Recombinant Human Anti-Human MLANA Antibody (H4) | ELISA, FC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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