Human Anti-PTPRC Recombinant Antibody (clone YTH54.12) (CAT#: FAMAB-1660CQ)
This product is a recombinant human antibody that recognizes CD45. The antibody was purified by affinity chromatography. It can be used in Depletion, IP, FC, IF.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/if_selected.jpg
Figure 2 Appendix
(Lymphoid tissue
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_3_2.jpg
(Lymphoid tissue
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_3_2.jpg
Figure 3 Lymph node
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_8_8.jpg
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, JURKAT, MOLT-4, THP-1, U-266/70, U-266/84, U-698, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081237-PTPRC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081237-PTPRC
Figure 4 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, JURKAT, MOLT-4, THP-1, U-266/70, U-266/84, U-698, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081237-PTPRC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081237-PTPRC
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human CD45
- Species Reactivity
- Human
- Clone
- YTH54.12
- Applications
- Depletion, IP, FC, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
- UniProt ID
- P08575
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-245LC | Human Anti-PTPRC Recombinant Antibody (TAB-245LC) | ELISA, FC | Human IgG2, κ |
| TAB-246LC | Human Anti-PTPRC Recombinant Antibody (TAB-246LC) | ELISA, FC | Human IgG2, κ |
| TAB-247LC | Human Anti-PTPRC Recombinant Antibody (TAB-247LC) | ELISA, FC | Human IgG2, κ |
| TAB-248LC | Human Anti-PTPRC Recombinant Antibody (TAB-248LC) | ELISA, FC | Human IgG2, κ |
| TAB-249LC | Human Anti-PTPRC Recombinant Antibody (TAB-249LC) | ELISA, FC | Human IgG2, κ |
Customer Reviews and Q&As
Customer Review
Q&As
Optimal for CD45 Research
Our lab focuses on leukocyte dynamics, and this antibody has been pivotal in our studies. Its high affinity and clear differentiation between CD45 isoforms have elevated the depth of our findings, enabling novel insights into immune cell function.
Essential for Autoimmune Studies
Studying autoimmune responses requires precision, and YTH54.12 provides just that. Its use has clarified CD45 involvement in autoimmune pathogenesis, supporting hypotheses with concrete experimental evidence.
User-Friendly Protocols
The ease of use associated with this antibody is exemplary. The detailed datasheet provides clarity on optimal usage conditions, resulting in high success rates and confidence in continuing purchases.
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For Research Use Only. Not For Clinical Use.
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