Recombinant Rabbit Anti-CXCL8 Capture Antibody (clone R02-3Z9) (CAT#: VS3-WK1690)
This antibody is a rabbit recombinant antibody against human CXCL8. It was developed by immunization of rabbit with recombinant human CXCL8 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R02-3Z9 and R02-9M5. The clone R02-3Z9 can be used as a capture antibody in ELISA analysis to identify human CXCL8.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/1010_F11_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/1010_F11_1_selected.jpg
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in non germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in non germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/ihc_selected.jpg
Figure 3 IF staining of human cell line GAMG
(Immunofluorescent staining of human cell line GAMG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/2058_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line GAMG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/2058_E8_1_blue_red_green.jpg
Figure 4 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_7_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_7_5.jpg
Figure 5 Testis
(Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_6_6.jpg
(Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_8_8.jpg
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_8_8.jpg
Figure 7 RNA cell line category: Group enriched (BJ hTERT+, GAMG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169429-CXCL8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169429-CXCL8
Specifications
- Immunogen
- Recombinant human CXCL8 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CXCL8
- Species Reactivity
- Human
- Clone
- R02-3Z9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- C-X-C Motif Chemokine Ligand 8; Monocyte-Derived Neutrophil Chemotactic Factor; Monocyte-Derived Neutrophil-Activating Peptide; Granulocyte Chemotactic Protein 1; Chemokine (C-X-C Motif) Ligand 8; Beta Endothelial Cell-Derived Neutrophil Activating Peptide; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Lymphocyte Derived Neutrophil Activating Peptide; Alveolar Macrophage Chemotactic Factor I; Tumor Necrosis Factor-Induced Gene 1; Neutrophil-Activating Peptide 1; T-Cell Chemotactic Factor; Interleukin 8; Emoctakin; GCP-1; MDNCF; MONAP
- Gene ID
- 3576
- UniProt ID
- P10145
- Long Name
- C-X-C Motif Chemokine Ligand 8
- Sequence Similarities
- Belongs to the intercrine alpha (chemokine CxC) family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.
- Protein Refseq
- NP_000575.1
- Function
- Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.
Also plays an important role in neutrophil activation.
Recommended Products
Detection antibody
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CXCL8"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-738-sdAb | Recombinant Anti-human CXCL8 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-201CL | Human Anti-CXCL8 Recombinant Antibody (TAB-201CL) | ELISA | Human IgG2 |
| TAB-701LC | Human Anti-CXCL8 Recombinant Antibody (TAB-701LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-701LC-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (TAB-701LC-S(P)) | ELISA | Human scFv |
| TAB-701LC-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (TAB-701LC-F(E)) | ELISA | Human Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-095LC | Recombinant Anti-Human CXCL8 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-164LC | Recombinant Anti-Human CXCL8 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-644CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL601) | ELISA, Neut | Mouse IgG1 |
| NEUT-645CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL602) | WB, ICC, Neut | Mouse IgG1 |
| NEUT-646CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL115) | FC, WB, IHC, Neut | Mouse IgG1 |
| NEUT-647CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-60) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-648CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-S2) | ELISA, Neut, WB | Mouse IgG2b, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-660CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone B-K8) | Block, ICFC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4128 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone SI199DS) | ELISA | Rabbit IgG |
| MOR-4624 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH137DS) | WB | Rabbit IgG |
| MOR-4625 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH138DS) | WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0059-YC-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (HPAB-N0059-YC-F(E)) | FuncS | Human Fab |
| HPAB-1101-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 656.35); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1102-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 197.2); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1103-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 81.1); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1104-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody; scFv Fragment (HPAB-1104-FY-S(P)) | ELISA | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1682-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1682-FY) | ELISA | Human IgG |
| HPAB-1683-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1683-FY) | ELISA | Human IgG |
| HPAB-1684-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1684-FY) | ELISA | Human IgG |
| MOB-Z052-YC | Mouse Anti-CXCL8 Recombinant Antibody (clone DEC.YC052) | ELISA, IF, WB | Mouse IgG |
| VS3-QX307 | Mouse Anti-CXCL8 Recombinant Antibody (clone 3A4-8B3-7H1) | IHC | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0664-YJ-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 5.12.14); scFv Fragment | ELISA, WB, Inhib, Antagonist | Mouse scFv |
| HPAB-S0084-YC-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 6G4.2.5); scFv Fragment | ELISA, Inhib | Mouse scFv |
| HPAB-S0085-YC-S(P) | Human Anti-CXCL8 Recombinant Antibody (clone ch6G4.2.5); scFv Fragment | ELISA, Inhib | Mouse scFv |
| HPAB-S0086-YC-S(P) | Human Anti-CXCL8 Recombinant Antibody (clone h6G4V11); scFv Fragment | ELISA, Inhib | Humanized scFv |
| HPAB-S0087-YC-S(P) | Human Anti-CXCL8 Recombinant Antibody (clone h6G4V11N35A); scFv Fragment | ELISA, Inhib, FuncS | Humanized scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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