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EDN1
Anti-EDN1 Recombinant Antibody Products
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- Species Reactivity: Human, Mouse, Canine, Porcine, Rat, Rabbit, Sheep
- Type: Mouse IgG1
- Application: Block, ELISA, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, RIA, WB
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- Recombinant Anti-Human EDN1 VHH Single Domain Antibody (NAB-818-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: FA, FC, ICC, ELISA
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For Research Use Only. Not For Clinical Use.
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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