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EDN1

Anti-EDN1 Products

Recombinant Mouse anti-Human EDN1 Monoclonal antibody (2D20) (MOB-0658CT)
- Species Reactivity: Human
- Application: ELISA
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Mouse Anti-EDN1 Recombinant Antibody (clone TR.ET.48.5) (NEUT-717CQ)
- Species Reactivity: Human, Mouse, Canine, Porcine, Rat, Rabbit, Sheep
- Type: Mouse IgG1
- Application: Block, ELISA, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, RIA, WB
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Recombinant Anti-Human EDN1 VHH Single Domain Antibody (NAB-818-VHH)
- Species Reactivity: Human
- Type: Llama VHH
- Application: FA, FC, ICC, ELISA
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Mouse Anti-EDN1 Recombinant Antibody (clone YC038); Fab Fragment (DrMAB-1051)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, LMNX
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Mouse Anti-EDN1 Recombinant Antibody (clone 4E6E5) (VS7-HM837)
- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: ICC, FCM
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Anti-EDN1 Immunohistochemistry Kit (VS-0525-XY2154)
- Species Reactivity: Human
- Target: EDN1
- Application: IHC
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Anti-Mouse EDN1 Immunohistochemistry Kit (VS-0525-XY2155)
- Species Reactivity: Human, Mouse, Rat, Porcine, Canine, Rabbit, Sheep
- Target: EDN1
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Related Signaling Pathways

TNF Signaling Pathway