Recombinant Mouse anti-Human EDN1 Monoclonal antibody (2D20)
CAT#: MOB-0658CT
Recombinant Mouse monoclonal antibody to Human EDN1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nucleoli & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31976/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and endothelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31976/66918_A_9_3_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human colon
Immunohistochemical staining of human colon shows plasma positivity in blood vessels.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_8_3_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nucleoli & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31976/321_D9_7_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 5 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, nucleoli & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31976/323_D9_1_blue_red_green.jpg
Normal Tissue
Figure 6 Lung
Alveolar cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Macrophages
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_1_4.jpg
Normal Tissue
Figure 7 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_8_3.jpg
Normal Tissue
Figure 8 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_8_4.jpg
Normal Tissue
Figure 9 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_9_5.jpg
Normal Tissue
Figure 10 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37291/87377_A_6_6.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, T-47d, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078401-EDN1
❮
❯
Specifications
- Immunogen
- Synthetic peptide: MDYLLMIFSL LFVACQGAPE T, corresponding to N terminal amino acids 1-21 of Human Endothelin 1
- Host Species
- Mouse
- Specificity
- This antibody is specific to the N-terminus of Endothelin. Reactivity to: Human ET-1 100%, Human ET-2 100%, Human ET-3 2%, Human big ET-1 100%, Porcine big ET-1 50%, VIC 6%
- Species Reactivity
- Human
- Clone
- 2D20
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: 0.1% Sodium Azide Constituents: PBS, pH 7.4
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- EDN1; endothelin 1; ET1; QME; PPET1; ARCND3; HDLCQ7; endothelin-1; preproendothelin-1;
- Gene ID
- 1906
- UniProt ID
- P05305
- Protein Refseq
- NP_001161791
- Function
- cytokine activity; endothelin A receptor binding; endothelin B receptor binding; endothelin B receptor binding; hormone activity;
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MOB-0658CT. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EDN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-818-VHH | Recombinant Anti-Human EDN1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1051 | Mouse Anti-EDN1 Recombinant Antibody (clone YC038); Fab Fragment | ELISA, LMNX | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-717CQ | Mouse Anti-EDN1 Recombinant Antibody (clone TR.ET.48.5) | Block, ELISA, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, RIA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-HM837 | Mouse Anti-EDN1 Recombinant Antibody (clone 4E6E5) | ICC, FCM | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2154 | Anti-EDN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2155 | Anti-Mouse EDN1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IHC, FuncS, Inhib, Cyt
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: WB, Neut, FuncS
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, IHC, FC, WB, IF, IA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
