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EGFR & ErbB-3

Anti-EGFR & ErbB-3 ProductsBackground
Anti-EGFR & ErbB-3 Products
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: FC, IP, ELISA, Neut, FuncS, IF
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- Derivation: Humanized (from rat)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: Neut, ELISA, IF, IP, FuncS, FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: FuncS, IF, Neut, ELISA, FC, IP
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- Derivation: Chimeric
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: FuncS, IF, Neut, ELISA, FC, IP
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: Neut
- Mouse Anti-EGFR Recombinant Antibody (clone CBL931) (NEUT-723CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IP, IHC, ICC, Neut
- Rabbit Anti-EGFR Recombinant Antibody (NEUT-724CQ) (NEUT-724CQ)
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- Species Reactivity: Human, Rat, Mouse
- Type: Rabbit IgG
- Application: IF, FC, WB, IP, Neut
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: Neut, ELISA, IF, IP, FuncS, FC
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- Derivation: Chimeric
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IHC, FC, IP, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Cetuximab (Gly-015CL)
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- CAS number: 205923-56-4
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn297 in Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
