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GP6
Anti-GP6 Recombinant Antibody Products
- Human Anti-GP6 Recombinant Antibody (clone F1201-20) (HPAB-1716-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-GP6 Recombinant Antibody (clone hGP 5C4) (HPAB-0133CQ)
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- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, FC, Inhib, FuncS
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- Human Anti-GP6 Recombinant Antibody (clone F1232-18-3) (HPAB-1715-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-GP6 Recombinant Antibody (clone F1232-7-1) (HPAB-1714-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-GP6 Recombinant Antibody (clone F1245-6-2) (HPAB-1713-FY)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, WB, IHC
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- Human Anti-GP6 Recombinant Antibody (clone F1245-5-1) (HPAB-1712-FY)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, WB, IHC
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- Human Anti-GP6 Recombinant Antibody (clone F1245-4-1) (HPAB-1711-FY)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, WB, IHC
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- Mouse Anti-GP6 Recombinant Antibody (clone 12A5) (FAMAB-0101JF)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC, FC
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- Human Anti-GP6 Recombinant Antibody (clone 10B12) (FAMAB-0288JF)
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- Derivation: Human phage display scFv library
- Species Reactivity: Human
- Type: Human IgG
- Application: FC, ELISA, FuncS
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- Human Anti-GP6 Recombinant Antibody (clone glenzocimab) (VS-0624-FY8)
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- Species Reactivity: Human
- Type: Human IgG1 kappa
- Application: Inhib
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- Human Anti-GP6 Recombinant Antibody (VS-0723-WK132) (VS-0723-WK132)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
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- Mouse Anti-GP6 Recombinant Antibody (HPAB-0004-CN) (HPAB-0004-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB
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- Human Anti-GP6 Recombinant Antibody (HPAB-0003-CN) (HPAB-0003-CN)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC, WB
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- Human Anti-GP6 Recombinant Antibody (HPAB-0002-CN) (HPAB-0002-CN)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC, WB
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- Mouse Anti-GP6 Recombinant Antibody (clone 38C4) (MOB-1438z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IF, IP
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- Human Anti-GP6 Recombinant Antibody (FAMAB-0289JF) (FAMAB-0289JF)
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- Derivation: Human phage display scFv library
- Species Reactivity: Human, mouse
- Type: Human IgG
- Application: FC, ELISA, FuncS
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- Human Anti-GP6 Recombinant Antibody (clone 10B12); scFv Fragment (FAMAB-0288JF-S(P))
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- Derivation: Human phage display scFv library
- Species Reactivity: Human
- Type: Human scFv
- Application: FC, ELISA, FuncS
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- Human Anti-GP6 Recombinant Antibody; scFv Fragment (HPAB-0003-CN-S(P)) (HPAB-0003-CN-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC, WB
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- Human Anti-GP6 Recombinant Antibody; scFv Fragment (HPAB-0002-CN-S(P)) (HPAB-0002-CN-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC, WB
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- Human Anti-GP6 Recombinant Antibody scFv Fragment (FAMAB-0289JF-S(P)) (FAMAB-0289JF-S(P))
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- Derivation: Human phage display scFv library
- Species Reactivity: Human, mouse
- Type: Human scFv
- Application: FC, ELISA, FuncS
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- Mouse Anti-GP6 Recombinant Antibody (clone 12A5); scFv Fragment (FAMAB-0101JF-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Human Anti-GP6 Recombinant Antibody (clone hGP 5C4); scFv Fragment (HPAB-0133CQ-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, Inhib, FuncS
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- Human Anti-GP6 Recombinant Antibody (clone F1232-18-3); scFv Fragment (HPAB-1715-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-GP6 Recombinant Antibody (clone F1232-7-1); scFv Fragment (HPAB-1714-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Mouse Anti-GP6 Recombinant Antibody (clone F1245-6-2); scFv Fragment (HPAB-1713-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IHC
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- Mouse Anti-GP6 Recombinant Antibody (clone F1245-5-1); scFv Fragment (HPAB-1712-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IHC
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- Mouse Anti-GP6 Recombinant Antibody (clone F1245-4-1); scFv Fragment (HPAB-1711-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IHC
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- Human Anti-GP6 Recombinant Antibody (clone F1201-20); scFv Fragment (HPAB-1716-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Mouse Anti-GP6 Recombinant Antibody; scFv Fragment (HPAB-0004-CN-S(P)) (HPAB-0004-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB
Compare
- Human Anti-GP6 Recombinant Antibody (clone hGP 5C4); Fab Fragment (HPAB-0133CQ-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, Inhib, FuncS
Compare
- Human Anti-GP6 Recombinant Antibody (clone 10B12); Fab Fragment (FAMAB-0288JF-F(E))
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- Derivation: Human phage display scFv library
- Species Reactivity: Human
- Type: Human Fab
- Application: FC, ELISA, FuncS
Compare
- Mouse Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0004-CN-F(E)) (HPAB-0004-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB
Compare
- Human Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0003-CN-F(E)) (HPAB-0003-CN-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC, WB
Compare
- Human Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0002-CN-F(E)) (HPAB-0002-CN-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC, WB
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1232-18-3); Fab Fragment (HPAB-1715-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1232-7-1); Fab Fragment (HPAB-1714-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1245-6-2); Fab Fragment (HPAB-1713-FY-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, IHC
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1245-5-1); Fab Fragment (HPAB-1712-FY-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, IHC
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1245-4-1); Fab Fragment (HPAB-1711-FY-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, IHC
Compare
- Mouse Anti-GP6 Recombinant Antibody (clone 12A5); Fab Fragment (FAMAB-0101JF-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
Compare
- Human Anti-GP6 Recombinant Antibody (clone F1201-20); Fab Fragment (HPAB-1716-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-GP6 Recombinant Antibody Fab Fragment (FAMAB-0289JF-F(E)) (FAMAB-0289JF-F(E))
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- Derivation: Human phage display scFv library
- Species Reactivity: Human, mouse
- Type: Human Fab
- Application: FC, ELISA, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Platelet glycoprotein VI (GPVI) is gaining attention as a potential target for the development of novel antiplatelet molecules with reduced bleeding risk. GPVI binding to vascular collagen triggers thrombosis, while the interaction of GPVI with fibrin promotes the growth and stabilization of thrombi.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Early spermatids, Macrophages, Inhibitory neurons, Excitatory neurons, Late spermatids, Cone photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEL, K-562, U-2 OS)
Interaction
Associated with Fc receptor gamma chain. The GPVI:FcRgamma complex is associated with the Src kinase family FYN and LYN (PubMed:10961879, PubMed:9295288). Interacts with TRAF4 (PubMed:20946164). Interacts with COL1A1, but not with COL4A4 (By similarity). (Microbial infection) Interacts with Staphylococcus aureus protein SSL5.
Molecular function
Receptor
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