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Anti-IL1B Recombinant Antibody Products

Anti-IL1B Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs provides a comprehensive portfolio of premium anti-IL-1B recombinant antibodies meticulously designed and rigorously validated to empower global researchers in their IL-1B-focused investigations. Our antibodies, characterized by exceptional specificity and sensitivity, exhibit outstanding performance across a spectrum of applications. Backed by robust validation data, these reagents facilitate the smooth progression of our customers’ research endeavors.

IL1B: A Significant Immunotherapy Target for Cancer

IL-1β is primarily generated by immune cells when activated by microbial ligands via Toll-like receptors (TLRs), complement proteins, and other signaling molecules such as TNF or IL-1. This cytokine is important in activating inflammatory responses and contributing to angiogenesis, which promotes tumor formation and metastasis, increasing the risk of cancer progression. As a result, developing treatments that specifically target IL-1β has emerged as a key cancer therapeutic tactic.

Alternative Names

Interleukin 1 beta; IL-1β; IL1-BETA; IL1beta; leukocytic endogenous mediator; leukocytic pyrogen; IL1F2; IL-1; mononuclear cell factor; lymphocyte activating factor.

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. The encoded protein plays a role in thymocyte proliferation and is involved in the inflammatory response.

Anti-IL1B rAb Products

Creative Biolabs provides a wide range of recombinant anti-IL1B antibodies that are carefully designed to provide high specificity and affinity and are available in various formats to facilitate a wide range of scientific research and therapeutic endeavors. By utilizing our extensive platform, we provide researchers with cutting-edge tools to advance immunology, oncology, and other relevant areas, as well as to support the development of new therapeutics.

Table 1. Featured anti-IL1B recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
ZG-0498J Mouse Anti-IL1B Recombinant Antibody (ZG-0498J) Human Mouse IgG WB, IHC, IF, ELISA
HPAB-N0148-YC Human Anti-IL1B Recombinant Antibody (clone 048Ab-4) Human Human IgG ELISA
HPAB-0859-FY Human Anti-IL1B Recombinant Antibody (HPAB-0859-FY) Human Human IgG Neut
HPAB-1228-FY Human Anti-IL1B Recombinant Antibody (HPAB-1228-FY) Human Human IgG Inhib, WB, Neut
HPAB-0332-FY Mouse Anti-IL1B Recombinant Antibody (clone 048-Ab-6) Human Mouse IgG In vivo, ELISA

Creative Quality Control

Creative Biolabs provides a wide selection of recombinant anti-IL1B antibodies that have undergone rigorous quality testing. Our cutting-edge facilities, along with our skilled scientists, meticulously construct each antibody to achieve targeted accuracy against IL1B. Moreover, we ensure that these antibodies have high specificity, strong binding affinity, and optimal performance across a wide range of research applications through applying them through rigorous testing.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-IL-1B antibody
(Cat# ZG-0498J, Creative Biolabs).

Fig.2 IHC analysis. (Creative Biolabs Original)Fig.2 IHC analysis of anti-IL-1B antibody
(Cat# ZG-0498J, Creative Biolabs).

Fig.3 IF analysis. (Creative Biolabs Original)Fig.3 IF analysis of anti-IL-1B antibody
(Cat# ZG-0498J, Creative Biolabs).

Customer Reviews

Excellent
Ce***a
Mouse Anti-IL1B Recombinant Antibody (ZG-0498J) (ZG-0498J)
We are very satisfied with the performance of the anti-IL-1B recombinant antibodies provided by Creative Biolabs in the immunofluorescence experiment. These antibodies showed excellent specificity and affinity, making our experimental results more reliable and accurate. In addition, Creative Biolabs' after-sales service is also impressive. Their technical team responded quickly, provided professional guidance, and helped solve problems encountered during the experiment. Such high-quality products and services have undoubtedly improved our research efficiency and are a trustworthy partner.
7/Aug/2023
Excellent
Se***n
Mouse Anti-IL1B Recombinant Antibody (clone 048-Ab-6) (HPAB-0332-FY)
We used Creative Biolabs' anti-IL-1B recombinant antibody in our in vivo experiments and were very satisfied with its performance. The antibody showed excellent specificity and strong affinity in the experiment, ensuring the accuracy and consistency of the experimental results. Furthermore, the antibody was shipped very quickly after purchase, and it was intact when it arrived in my hands. The accompanying instructions were detailed and easy to understand.
20/Nov/2023
Excellent
Ja***n
Human Anti-IL1B Recombinant Antibody (HPAB-0978WJ) (HPAB-0978WJ)
In our ELISA experiments, we employed Creative Biolabs' anti-IL-1B recombinant antibodies and were highly impressed by their exceptional performance. These antibodies demonstrated remarkable specificity and strong affinity in the detection of IL-1B, consistently delivering accurate and reliable results. Furthermore, Creative Biolabs' antibodies significantly enhanced the sensitivity of our ELISA assays, enabling us to detect even minute concentrations of IL-1B. Their contribution to our research has been invaluable, solidifying their position as indispensable tools within our laboratory.
29/Jun/2024

rAb Production

Creative Biolabs produces a consistent supply of superior anti-IL1B antibodies via cutting-edge genetic engineering methods.

Featured Anti-IL1B Recombinant Antibody Production PlatformsFig.4 Milligram-scale. (Creative Biolabs Original)
Fig.4 Milligram-scale anti-IL1B recombinant antibody production.

Fig.5 Gram-scale. (Creative Biolabs Original)Fig.5 Gram-scale anti-IL1B recombinant antibody production.

rAb Modalities

Creative Biolabs offers an extensive selection of premium anti-IL1B recombinant antibodies in multiple formats, designed to cater to the diverse needs of researchers worldwide.

Fig.6 IL1B antibody production and modalities. (Creative Biolabs Original)Fig.7 Full-length anti-IL1B recombinant antibody production and modalities.

IL1B-Targeted Drug Information

Table 2. Public drug targeting IL1B.

Company Research Phase Classification Condition
Bristol-Myers Squibb (Originator)
Novartis (Originator)
Radboud Universiteit Nijmegen
Universitaet Zuerich
Universität Zürich (Universitaet Zuerich)
Launched - 2009 Cancer Immunotherapy
Human Monoclonal Antibodies
Adult onset Still disease
Aneurysm, abdominal aortic
Arthritis
Arthritis, gouty
Arthritis, juvenile idiopathic
Asthma
Autoimmune disease
Behcet's disease
Cancer, lung (non-small cell) (NSCLC)
Cancer, pancreas
Cancer, solid tumor
Chronic obstructive pulmonary disease (COPD)
Cryopyrin-associated periodic syndromes
Cytokine release syndrome
Diabetes type 1
Diabetes type 2
Familial Mediterranean fever
Gout
Hypoglycemia
Kawasaki disease
Macular degeneration
Melanoma
Mevalonate kinase deficiency
Osteoarthritis, knee
Other cardiovascular disorders
Periodic fever syndrome (autoinflammatory syndrome)
Pyoderma gangrenosum
Retinopathy, diabetic
Rheumatoid arthritis
Sarcoidosis, pulmonary
Schnitzler syndrome
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19)
Sickle cell anemia
Still disease
Synkinesis
Thalassemia, beta
TNF receptor associated periodic syndrome (TRAPS)
Triple negative breast cancer
Urticaria, idiopathic
Vasculitis
Wet macular degeneration (exudative)
Abbott
AbbVie (Originator)
Phase III Bispecific Antibodies
Humanized Monoclonal Antibodies
Hidradenitis suppurativa
Osteoarthritis, hand
Osteoarthritis, knee
Ulcerative colitis
Flame Biosciences (Originator) Phase II Antibodies
Cancer Immunotherapy
Cancer, lung (non-small cell) (NSCLC)
Novartis (Originator) Phase II Bispecific Antibodies Colitis
Coronary heart disease
Hidradenitis suppurativa
Inflammatory disorders
Metabolic and nutritional genetic disorders
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19)
Lilly (Originator) Phase II Antibodies Diabetes type 2
Rheumatoid arthritis
Amgen (Originator)
AstraZeneca
MedImmune (AstraZeneca)
Phase II Human Monoclonal Antibodies Inflammatory disorders
Rheumatoid arthritis
Sunshine Guojian Pharmaceutical (Originator) Phase I/II Humanized Monoclonal Antibodies Arthritis, juvenile idiopathic
Gout
Periodic fever syndrome (autoinflammatory syndrome)
Buzzard Pharmaceuticals
Carisma Therapeutics (Originator)
Eleven Biotherapeutics (Carisma Therapeutics)
Phase I/II Fusion Proteins
Polypeptides, from 41 AA
Cancer, solid tumor
Conjunctivitis, allergic
Dry eye
Tavotek (Originator) Phase I Human Monoclonal Antibodies Inflammatory disorders
Novartis
Servier
Xoma (Originator)
Discontinued Cancer Immunotherapy
Humanized Monoclonal Antibodies
Acne
Acute coronary syndrome
Arthritis
Arthritis, juvenile idiopathic
Behcet's disease
Cancer, colorectal
Cancer, gastroesophageal junction
Cancer, kidney (renal cell carcinoma)
Cardiovascular Disorders
Dermatomyositis
Diabetes type 1
Diabetes type 2
Diabetic nephropathy
Ear Disorders
Giant cell arteritis
Gout
Osteoarthritis, hand
Pustular psoriasis (generalized)
Pyoderma gangrenosum
Rheumatoid arthritis
Schnitzler syndrome
Scleritis
Uveitis

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

As a leading antibody manufacturer, Creative Biolabs is devoted to providing a diverse range of high-quality anti-IL1B recombinant antibodies. Please do not hesitate to contact us if you want further information or have any queries about our antibodies.

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