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Anti-IL23 Recombinant Antibody Products

Anti-IL23 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs offers a large range of premium, recombinant anti-IL23 antibodies, designed for best performance in demanding research uses. By using cutting-edge engineering methods, these antibodies show remarkable specificity, strong stability, and great efficacy, guaranteeing consistent and repeatable findings for important in vitro and in vivo studies.

IL23: A Potential Target for Inflammatory Diseases

Crucially a member of the IL-12 cytokine family, Interleukin-23 (IL-23) controls a variety of immune-mediated inflammatory disorders (IMIDs), including psoriasis, psoriatic arthritis, and inflammatory bowel disease. Like a rheostatic control or master switch, IL-23 is a vital regulating cytokine that drives and sustains a strong proinflammatory milieu and helps to alter immune cell behavior, therefore controlling the beginning and continuation of these IMIDs. This essential function emphasizes IL-23's great potential as a therapeutic target to solve the fundamental inflammatory processes in these diseases.

Alternative Names

Interleukin-23; IL-23; P19; SGRF; IL-23A; IL23P19

Background

It is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the IL23A (IL-23p19) subunit.

Anti-IL23 rAb Products

Creative Biolabs provides a range of recombinant anti-IL23 antibodies that have been meticulously crafted to ensure exceptional specificity and binding strength. From basic immunological and cancer biology studies to the creation of new therapeutic approaches, these flexible antibodies, available in several forms, cater to a wide spectrum of uses. Using a strong platform, Creative Biolabs offers cutting-edge technologies to enable researchers to push the envelope of knowledge and hasten the development of novel treatments.

Table 1. Featured anti-IL23 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
TAB-008ML Anti-Human IL23A Recombinant Antibody (Brazikumab) Human Human IgG2, λ ELISA, IHC, FC, IP, IF, Inhib, PK
TAB-620LC Anti-human IL23A Recombinant Antibody Human Humanized antibody ELISA
TAB-420CL Anti-Human IL23A Recombinant Antibody Human Human FuncS
TAB-875 Anti-Human IL23 Recombinant Antibody (Tildrakizumab) Human Mouse IgG1 - kappa Neut, ELISA, IF, IP, FuncS, FC, ICC
HPAB-0275LY Human Anti-IL23 Recombinant Antibody (HPAB-0275LY) Human Humanized IgG1 Inhib, ELISA

Creative Quality Control

Creative Biolabs provides a wide range of strictly quality-regulated anti-IL23 recombinant antibodies. Every antibody is exactly made to target IL23 with great accuracy, and extensive testing and validation ensures remarkable specificity, strong binding affinity, and best performance for many different research uses.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-IL23 antibody
(Cat# TAB-620LC, Creative Biolabs).

Fig.2 DB analysis. (Creative Biolabs Original)Fig.2 DB analysis of anti-IL23 antibody
(Cat# TAB-620LC, Creative Biolabs).

Fig.3 ELISA analysis. (Creative Biolabs Original)Fig.3 ELISA analysis of anti-IL23 antibody
(Cat# TAB-620LC, Creative Biolabs).

Fig.4 HPLC analysis. (Creative Biolabs Original)Fig.4 HPLC analysis of anti-IL23 antibody
(Cat# TAB-620LC, Creative Biolabs).

Fig.5 WB analysis. (Creative Biolabs Original)Fig.5 WB analysis of anti-IL23 antibody
(Cat# TAB-008ML, Creative Biolabs).

Fig.6 ELISA analysis. (Creative Biolabs Original)Fig.6 ELISA analysis of anti-IL23 antibody
(Cat# TAB-008ML, Creative Biolabs).

Customer Reviews

Excellent
Ma***y
Mouse Anti-IL23 Recombinant Antibody (clone m21D1) (HPAB-0363-WJ)
Our in vitro investigations on T cell activation using Creative Biolabs' anti-IL23 antibody have consistently produced very good findings. Excellent specificity is shown; our study depends on minimum cross-reactivity with other IL-12 family members. The performance of the antibody is quite consistent, hence we have been able to confidently repeat our studies. The constancy in quality has spared us much time and money. Excellent!
17/Apr/2021
Excellent
Jo***n
Human Anti-IL23 Recombinant Antibody (clone ABT-874) (HPAB-3397LY)
Creative Biolabs supplied us with an antibody format that was precisely tailored to our requirements. The binding affinity was remarkable, and in our animal models, we found a notable decrease in illness indicators. Their experts kindly helped us choose the correct antibody and provided us with thorough characterization data, thereby guiding us. The quality of the antibodies, together with their first-rate service, has exceeded our expectations.
11/Aug/2022
Excellent
Da***l
Human Anti-IL23 Recombinant Antibody (clone ABT-874); scfv Fragment (HPAB-3397LY-S(P))
For our flow cytometers and ELISA tests, we ordered biotinylated anti-IL23 antibody. Showing outstanding signal-to-noise ratios, the antibody performed perfectly in both uses. The several formats offered by Creative Biolabs let us readily include the antibody into our current procedures. When we had some enquiries about the ideal dilution for our particular experiment, the technical support team answered fast with thorough advice and useful recommendations. The antibody quality is really excellent, and the customer service was first-rate.
21/Sep/2023

rAb Production

Creative Biolabs leverages advanced genetic engineering techniques to ensure a reliable and continuous supply of high-quality anti-IL23 antibodies.

Featured Anti-IL23 Recombinant Antibody Production PlatformsFig.7 Milligram-scale. (Creative Biolabs Original)
Fig.7 Milligram-scale anti-IL23 recombinant antibody production.

Fig.8 Gram-scale. (Creative Biolabs Original)Fig.8 Gram-scale anti-IL23 recombinant antibody production.

rAb Modalities

Creative Biolabs offers a comprehensive selection of premium anti-IL23 recombinant antibodies, available in multiple formats, designed to cater to the diverse needs of researchers worldwide.

Fig.9 IL23 antibody production and modalities. (Creative Biolabs Original)Fig.9 Full-length anti-IL23 recombinant antibody production and modalities.

IL23-Targeted Drug Information

Table 2. Public drug targeting IL23.

Company Research phase Classification Condition
Alvotech (Originator)
Fuji Pharma
JAMP Pharma
STADA
Teva
Launched - 2024 Follow-on Products
Human Monoclonal Antibodies
Arthritis, psoriatic
Crohn's disease
Inflammatory disorders
Plaque psoriasis
Psoriasis
Amgen (Originator) Launched - 2024 Biosimilars
Follow-on Products
Human Monoclonal Antibodies
Arthritis, psoriatic
Crohn's disease
Inflammatory disorders
Juvenile arthritis, psoriatic
Plaque psoriasis
Ulcerative colitis
Almirall
China Medical System (CMS)
Garvan Institute
Merck & Co (Originator)
Merck & Co. (Merck & Co)
Sun Pharma
Launched - 2018 Cancer Immunotherapy
Humanized Monoclonal Antibodies
Arthritis, psoriatic
Osteosarcoma
Plaque psoriasis
Psoriasis
Vitiligo
Centocor Ortho Biotech (Janssen)
Janssen
Janssen Biotech (Janssen)
Janssen-Cilag (Janssen)
Janssen Pharmaceutical (JP)
Janssen Research & Development (Janssen)
MorphoSys (Originator)
Taiho
Launched - 2017 Cancer Immunotherapy
Human Monoclonal Antibodies
Arthritis, psoriatic
Celiac disease
Crohn's disease
Giant cell arteritis
Hidradenitis suppurativa
Juvenile arthritis, psoriatic
Plaque psoriasis
Polyp, adenomatous
Psoriasis
Pustular psoriasis (generalized)
Pustular psoriasis (palmoplantar pustulosis)
Rheumatoid arthritis
Ulcerative colitis
Bristol-Myers Squibb (Originator)
Centocor (Janssen)
Centocor Ortho Biotech (Janssen)
Charité Universitätsmedizin Berlin (Charite Universitaetsmedizin Berlin)
Janssen
Janssen Biotech (Janssen)
Janssen-Cilag (Janssen)
Janssen-Ortho (Janssen)
Janssen Pharmaceutical (JP)
Janssen Pharmaceuticals (Janssen)
Janssen Research & Development (Janssen)
Johnson & Johnson
Massachusetts General Hospital
Mitsubishi Tanabe Pharma
National Eye Institute (NEI)
National Institute Allergy Infect Dis
Rockefeller University
Launched - 2008 Human Monoclonal Antibodies Arthritis, psoriatic
Atopic dermatitis
Axial spondyloarthritis, radiographic (Ankylosing spondylitis)
Crohn's disease
Dermatomyositis
Diabetes type 1
Giant cell arteritis
Hidradenitis suppurativa
Leukocyte adhesion deficiency type 1
Multiple sclerosis
Pityriasis rubra pilaris
Plaque psoriasis
Polymyositis
Pouchitis
Primary biliary cholangitis
Psoriasis
Rheumatoid arthritis
Sarcoidosis
Spondyloarthritis
Systemic lupus erythematosus
Ulcerative colitis
Uveitis
Samsung Bioepis (Originator)
Sandoz
Registered - 2024 Follow-on Products
Human Monoclonal Antibodies
Arthritis, psoriatic
Autoimmune disease
Crohn's disease
Plaque psoriasis
Ulcerative colitis
Bioeq
Formycon (Originator)
Fresenius Kabi
Pre-Registered Follow-on Products
Human Monoclonal Antibodies
Immune-mediated inflammatory disease
Immunological Disorders
Inflammatory disorders
Plaque psoriasis
Dong-A ST (Originator)
Intas Pharmaceuticals
Meiji Seika Pharma
STgen Bio
Pre-Registered Follow-on Products
Human Monoclonal Antibodies
Immune-mediated inflammatory disease
Inflammatory disorders
Plaque psoriasis
Qyuns Therapeutics (Originator) Phase III Follow-on Products
Human Monoclonal Antibodies
Plaque psoriasis
Biomm
Bio-Thera Solutions (Originator)
Hikma
Pharmapark
Phase III Follow-on Products
Human Monoclonal Antibodies
Psoriasis

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

For detailed information or to discuss your specific anti-IL23 recombinant antibody needs, our team is readily available to assist you. Please reach out to us at your convenience.

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