Anti-SOS1 Recombinant Antibody Products

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Anti-SOS1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs proudly delivers an advanced portfolio of anti-SOS1 recombinant antibody products, meticulously developed to support and enhance the endeavors of researchers and pharmaceutical enterprises globally. These high-quality antibodies are characterized by their unparalleled specificity and robust affinity, thereby constituting indispensable reagents for the advancement of drug discovery initiatives and the development of therapeutic interventions targeting critical disease pathways.

SOS1: A Critical Target for Cancer Therapy

Son of Sevenless homolog 1 (SOS1) is a crucial guanine nucleotide exchange factor (GEF) that plays a pivotal role in activating the RAS-MAPK signaling pathway, a central regulator of cell growth, differentiation, and survival. Extensive research highlights SOS1's involvement in numerous human cancers, where its aberrant activity drives oncogenic signaling. Consequently, targeting SOS1 has emerged as a compelling strategy for developing novel anti-cancer therapies, offering a promising avenue to disrupt tumor progression and overcome drug resistance.

Alternative Names

Son of sevenless homolog 1; GF1; GGF1; GINGF; HGF; NS4; SOS Ras/Rac guanine nucleotide exchange factor 1; SOS-1.

Background

The SOS1 gene is an oncogene discovered in 2002 and is one of the HCF pathogenic genes that have been successfully cloned and identified. The SOS1 gene is located in the short arm 21 regions of chromosome 2 and plays an oncogene role in tumor cells. Domestic studies have shown that this gene is positively correlated with gingival fibromatosis and myocardial disease. Foreign studies have shown that SOS1 is positively correlated with the malignant degree of glioma and the proliferation of tumor cells. The role of SOS1 in carcinoid genes in tumor cells has attracted more and more attention. SOS1 can interact with MAPK pathway to introduce exogenous genes into the nucleus to regulate cell proliferation. With knockout of SOS1 gene or inhibition of SOS1 gene expression, it can be found that the proliferation of tumor cells is inhibited, and even the apoptosis of tumor cells is caused. SOS1 also interacts with a variety of genes, which are key to the regulation of tumor growth by other genes, but few have found a complete chain of action from the initiating factor to the eventual abnormal proliferation of the tumor. SOS2 is adjacent to the SOS1 locus. The positional structure determines the function, so SOS2 plays an oncogene function similar to SOS1 in tumors and inhibits the proliferation of tumor cells as long as the expression of SOS1/SOS2 is inhibited.

Anti-SOS1 rAb Products

At Creative Biolabs, our recombinant anti-SOS1 antibody products are engineered with superior precision, offering exceptional specificity and high affinity for the SOS1 protein. Produced through advanced recombinant technology, these antibodies ensure lot-to-lot consistency and minimal batch variation, critical for reliable and reproducible research outcomes. Their strong performance makes them suitable for a broad range of applications, including fundamental research and preclinical drug development.

Table 1. Featured anti-SOS1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs employs stringent quality control measures to guarantee the highest standards for our anti-SOS1 recombinant antibodies. Each batch undergoes rigorous validation, including comprehensive binding assays, functional analyses, and purity assessments. This careful attention to detail guarantees high performance, repeatability, and dependability, giving researchers confidence in their experimental findings.

Customer Reviews

Excellent

Em***y
Recombinant Mouse anti-Human SOS1 Monoclonal antibody (TPT-2) (MOB-1902CT)

The anti-SOS1 recombinant antibody from Creative Biolabs has significantly streamlined our research. Its exceptional specificity and low background noise have allowed us to obtain clear, reliable data in our western blot experiments, accelerating our understanding of SOS1's role in cancer signaling. A truly indispensable tool for our lab!

17/May/2023

Excellent

Ku***y
Hi-Affi™ Recombinant Rabbit Anti-SOS1 Monoclonal Antibody (DS3372AB) (MOR-3372)

We've been consistently impressed with the performance of Creative Biolabs' anti-SOS1 antibodies in our functional assays. The high affinity and consistent activity across different batches have been crucial for our drug screening efforts, leading to more robust and dependable results.

3/Mar2024

Excellent

Mi***l
Recombinant Mouse anti-Human SOS1 Monoclonal antibody (TPT-2) (MOB-1902CT)

For our therapeutic development program, the anti-SOS1 antibody's performance in in vivo studies has been outstanding. Its stability and efficacy have exceeded our expectations, contributing significantly to our preclinical success. Creative Biolabs delivers products that genuinely make a difference in translational research.

10/Oct/2024

rAb Production

Our anti-SOS1 recombinant antibodies are produced using state-of-the-art mammalian expression systems, ensuring optimal post-translational modifications and biological activity. This advanced production platform allows for large-scale manufacturing while maintaining exceptional purity and structural integrity, meeting the demands of both research and industrial applications.

Featured Anti-SOS1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-SOS1 recombinant antibody production.

Fig.2 Gram-scale anti-SOS1 recombinant antibody production.

rAb Modalities

These versatile anti-SOS1 recombinant antibodies are available in multiple modalities, including various isotype formats and conjugation options, providing flexibility for diverse experimental designs.

Fig.3 Full-length anti-SOS1 recombinant antibody production and modalities.

SOS1-Targeted Drug Information

Table 2. Public drug targeting SOS1.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is dedicated to supporting your scientific endeavors with premium research tools. Our anti-SOS1 recombinant antibody products demonstrate our dedication to innovation and excellence. To learn more about how these antibodies can accelerate your research or to discuss custom solutions, please do not hesitate to contact us directly.

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Related Signaling Pathways

ErbB Signaling Pathway

FcεR1 Signaling Pathway

MAPK Signaling Pathway

mTOR Signaling Pathway

PPAR Signaling Pathway

Ras Signaling Pathway

TCR Signaling Pathway