+ Filter
Loading...
Custom Services order now ship next day

SOX2

Anti-SOX2 Recombinant Antibody Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


SOX2 is a transcription factor belonging to the Sox family. It contains a highly conserved DNA - binding domain called the HMG (high - mobility group) box. Structurally, the HMG box allows SOX2 to bind to specific DNA sequences in the promoter and enhancer regions of target genes.
SOX2
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Muller glia cells, Basal squamous epithelial cells, Squamous epithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, HAP1, NTERA-2, U-251 MG)

Interaction

Interacts with ZSCAN10 (By similarity). Interacts with SOX3 and FGFR1 (By similarity). Interacts with GLIS1 (PubMed:21654807). Interacts with POU5F1; binds synergistically with POU5F1 to DNA (By similarity).

Molecular function

Activator, Developmental protein, DNA-binding

More Types Infomation
  • 0
  • 0
Cart
    Go to compare

    Go to compare