Loading...

TLR2

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
  • Rabbit Anti-TLR2 Antibody (CBMAB-0271MC)

    • Species Reactivity: Reacts with: Human
      Predicted to work with: Mouse, Rat, Sheep, Horse, Dog, Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Gorilla, Chinese Hamster
    • Application: WB

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

© 2007 - 2019 Creative BioLabs All Rights Reserved
  • 0
  • 0

Cart