Recombinant Anti-TLR2 Intrabody [+36 GFP] (CAT#: IAB-B030(G))

Recombinant anti-TLR2 intrabody in fusion with +36GFP works within cells towards TLR2, expressed in CHO cells. Intracellular antibodiess expressed and retained inside the endoplasmatic reticulum (ER-intrabodies) are applied to block translocation of secreted and cell surface molecules from the ER to the cell surface resulting in functional inhibition of the target protein. since cell activation via TLR2 and other pattern recognition receptors (PRRs) contributes to sepsis pathology and chronic inflammation both relying on overamplification of an immune response.


Specific Inquiry
  • Size:
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  • Endotoxin:
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Immunogen
  • Toll-like receptor (TLR) 2
  • Host Species
  • murine
  • Type
  • scFv-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Applications
  • Antibody assay: Enzyme-linked Immunosorbent Assay; Western blot; Immunocytochemistry; Functional studies

Product Property

  • Purity
  • Purity>95% by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • CD282; CD282 antigen; TIL 4; TLR 2; TLR2; TLR2_HUMAN; Toll like receptor 2; Toll like receptor 2 precursor; Toll-like receptor 2; Toll/interleukin 1 receptor like 4; Toll/interleukin 1 receptor like protein 4; Toll/interleukin receptor like protein 4; Tol

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TLR2"

Intrabody

CAT Product Name Application Type
IAB-B030(A) Recombinant Anti-TLR2 Intrabody [(D-Arg)9] ICC, Neut, FuncS scFv-(D-Arg)9
IAB-B030(T) Recombinant Anti-TLR2 Intrabody [Tat] IF, FC, WB, FuncS scFv-Tat

Humanized Antibody

CAT Product Name Application Type
TAB-269CQ Human Anti-TLR2 Recombinant Antibody (TAB-269CQ) ELISA, FC, FuncS, IP, Inhib Humanized IgG1, κ
TAB-269CQ-S(P) Human Anti-TLR2 Recombinant Antibody; scFv Fragment (TAB-269CQ-S(P)) ELISA, FC, WB, IP Humanized scFv
TAB-269CQ-F(E) Human Anti-TLR2 Recombinant Antibody; Fab Fragment (TAB-269CQ-F(E)) ELISA, FC, WB, IP Humanized Fab

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0588MZ Chicken Anti-TLR2 Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2031CQ Mouse Anti-TLR2 Recombinant Antibody (clone TL2.1) FC, IP, Block, IHC, WB Mouse IgG2a, κ

Neutralizing Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3585 Rabbit Anti-TLR2 Recombinant Antibody (clone DS3585AB) WB, ICC, IP Rabbit IgG

scFv Fragment Antibody

Fab Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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