A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer (CAT#: MHC-LC036)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of p53-derived peptide of GLAPPQHLIRV sequence covering 187-197 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Subcellular Location

Normal Tissue

RNA Expression


Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • p53
  • Antigen Species
  • Human
  • Peptide
  • GLAPPQHLIRV
  • Range
  • 187-197
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
  • Alternative Names
  • TP53; Tumor protein p53; P53; BCC7; LFS1; TRP53

Related Resources

  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TP53"

scFv Fragment Antibody

CAT Product Name Application Type
DrMAB-994 Recombinant anti-TP53 antibody svFv Fragment ELISA, Agonist scFv
HPAB-0001-YC-S(P) Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); scFv Fragment IHC, WB, ELISA Mouse scFv
HPAB-0002-YC-S(P) Mouse Anti-TP53 Recombinant Antibody (clone 240); scFv Fragment IP, ELISA Mouse scFv
HPAB-0003-YC-S(P) Mouse Anti-TP53 Recombinant Antibody (clone 246); scFv Fragment IP, ELISA Mouse scFv
HPAB-0662-YJ-S(P) Mouse Anti-TP53 Recombinant Antibody (clone Ab421); scFv Fragment ELISA Mouse scFv

Single-domain Antibody

CAT Product Name Application Type
PNBL-072 Recombinant Anti-p53 VHH Single Domain Antibody (Nb139) Inhib, IP, WB, ELISA, FuncS Llama VHH
HPAB-0746-YJ-VHH Camelid Anti-TP53 Recombinant Single Domain Antibody (CBP71YJ) ELISA Camelid VHH

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC037 A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer FCM
MHC-LC038 A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer FCM
MHC-LC051 A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer FCM
MHC-LC052 A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer FCM
MHC-LC053 A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3644 Rabbit Anti-TP53 Recombinant Antibody (clone DS3644AB) IHC-P Rabbit IgG
MOR-4524 Rabbit Anti-TP53 Recombinant Antibody (clone TH32DS) WB, IF, ICC Rabbit IgG
MOR-4698 Rabbit Anti-TP53 Recombinant Antibody (clone TH212DS) WB, IF, ICC, FC, ChIP, FRET Rabbit IgG

Model Organism Antibody

CAT Product Name Application Type
MD-ZBF-YC001 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-1.1) WB, ICC Mouse antibody
MD-ZBF-YC002 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-2.1) WB, ICC, IHC Mouse antibody
MD-ZBF-YC003 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-3.1) WB, ICC Mouse antibody
MD-ZBF-YC004 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-4.1) WB, ICC Mouse antibody
MD-ZBF-YC005 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-5.1) WB, ICC, IHC Mouse antibody

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0001-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); Fab Fragment IHC, WB, ELISA Mouse Fab
HPAB-0002-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 240); Fab Fragment IP, ELISA Mouse Fab
HPAB-0003-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 246); Fab Fragment IP, ELISA Mouse Fab
HPAB-M0287-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 6C4); Fab Fragment ELISA Mouse Fab
HPAB-1568WJ-F(E) Mouse Anti-TP53 Recombinant Antibody; Fab Fragment (clone 11D3) ELISA, WB Mouse Fab

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0633CQ Mouse Anti-TP53 Recombinant Antibody (clone p53-11) WB Mouse IgG

Recombinant Antibody

CAT Product Name Application Type
MRO-1147-CN Mouse Anti-TP53 Recombinant Antibody (clone 6B2) WB Mouse IgG2b
MRO-1148-CN Mouse Anti-TP53 Recombinant Antibody (clone 6B5) WB Mouse IgG1
MRO-1149-CN Mouse Anti-TP53 Recombinant Antibody (clone C8-A11) WB, IF, IHC Mouse IgG1
MRO-1150-CN Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-418) WB, IF Rabbit IgG
MRO-1151-CN Rabbit Anti-TP53 Recombinant Antibody (clone SY010-6) WB, IF, IHC, IP Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
WBWestern Blot

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