Anti-CD20 antibody is a Human antibody of IgG1 κ class that binds to an CD20.
Host: Human
Isotype: IgG
Applications: WB, ELISA, IF, FuncS, Apop, BA
Figure 1 Ofatumumab and rituximab exhibit modest direct antitumor activity against MCL cell lines.
MCL cell lines were utilized in alamarBlue reduction assays to investigate the direct antilymphoma activity of each antibody. Each antibody exhibited a time-dependent decrease in MCL cell viability following exposure to 10 μg/mL of each respective antibody in the presence of a cross-linking IgG antibody. With the exception of the Mino cell line at the 72-hour time point, all cell lines demonstrated similar degrees of direct antitumor activity with ofatumumab and rituximab at the dose tested (*, P < 0.05).
Barth, M. J., Mavis, C., Czuczman, M. S., & Hernandez-Ilizaliturri, F. J. (2015). Ofatumumab exhibits enhanced in vitro and in vivo activity compared to rituximab in preclinical models of mantle cell lymphoma. Clinical Cancer Research, 21(19), 4391-4397.
Figure 2 Ofatumumab induces significantly higher levels of CDC-associated cell lysis than rituximab.
MCL tumor cell lines were tested for CDC cell lysis using a 51Cr release assay with human serum from normal healthy donors as a source of complement. In all MCL cell lines tested, with the exception of Granta, ofatumumab was more effective than rituximab at inducing CDC lysis at a dose of 10 μg/mL. (*, P < 0.05).
Barth, M. J., Mavis, C., Czuczman, M. S., & Hernandez-Ilizaliturri, F. J. (2015). Ofatumumab exhibits enhanced in vitro and in vivo activity compared to rituximab in preclinical models of mantle cell lymphoma. Clinical Cancer Research, 21(19), 4391-4397.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
NAB-913-sdAb | Recombinant Anti-human MS4A1 VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
HPAB-M0704-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD25) | ELISA, FuncS | Camelid VHH |
HPAB-M0705-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD16) | ELISA | Camelid VHH |
HPAB-M0706-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone R3CD7) | ELISA | Camelid VHH |
HPAB-M0707-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD78) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
TAB-1665CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1665CL) | CDC | Chimeric (mouse/human) IgG |
TAB-1633CL-S(P) | Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5) | FC | Chimeric antibody (mouse/human) |
TAB-1634CL-S(P) | Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5-DXL) | FC, Apop, CDC, ADCC, Inhib | Chimeric antibody (mouse/human) |
TAB-1656CL-S(P) | Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch2B8) | FC, CMCD, ADCC, Activ, Inhib, Depletion | Chimeric antibody (mouse/human) |
PABX-026 | Recombinant Human Anti-CD20 Antibody (C2H7) | FuncS | IgG |
CAT | Product Name | Application | Type |
TAB-1677CL | Anti-Human MS4A1 Recombinant Antibody (IBI-301) | PK | Humanized antibody |
TAB-1694CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1694CL) | CDC | Humanized IgG |
TAB-1695CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1695CL) | Cyt, ELISA, FuncS | Humanized IgG |
TAB-1696CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1696CL) | Cyt, ELISA, FuncS | Humanized IgG |
TAB-1697CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1697CL) | Cyt, ELISA, FuncS | Humanized IgG |
CAT | Product Name | Application | Type |
TAB-1703CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1703CL) | FC, CDC, IP | Human IgG1, κ |
TAB-1648CL-F(E) | Anti-MS4A1 Recombinant Antibody Fab Fragment (MEDI-552) | Inhib | |
TAB-1654CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1654CL-F(E)) | FC, Apop | Human Fab |
TAB-1655CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1655CL-F(E)) | ELISA | Human Fab |
TAB-1676CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1676CL-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
TAB-1659CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K0924) | Apop, FuncS | |
TAB-1660CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1K1712) | Apop, FuncS | |
PABX-026-S (P) | Recombinant Mouse Anti-CD20 Antibody scFv Fragment (C2H7) | WB, ELISA, FuncS | scFv |
PABX-028-S (P) | Recombinant Human Anti-CD20 Antibody scFv Fragment (Ofatumumab) | WB, ELISA, IF, FuncS | scFv |
TAB-007ML | Anti-Canine MS4A1 Recombinant Antibody (Blontuvetmab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ, λ |
CAT | Product Name | Application | Type |
Gly-059LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
Gly-060LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Gly-062LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
Gly-063LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
Gly-067LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA, FC | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
Gly-134LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-135LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-136LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-137LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-138LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
Gly-142LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
Gly-155LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
Gly-171LC | Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
MHC-LC066 | A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC067 | A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC068 | A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC4347 | PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
NEUT-1751CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) | Neut, FuncS | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
MOR-2295 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB) | IHC-Fr, IHC-P | Rabbit IgG |
MOR-4024 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
HPAB-0018-FY | Human Anti-MS4A1 Recombinant Antibody (HPAB-0018-FY) | FC | Humanized IgG1 |
HPAB-0021-FY | Human Anti-MS4A1 Recombinant Antibody (clone hu3D9) | FC | Humanized IgG |
HPAB-0683-CN | Human Anti-MS4A1 Recombinant Antibody (clone Rmut8) | ELISA, FC | Chimeric (mouse/human) IgG |
HPAB-0684-CN | Human Anti-MS4A1 Recombinant Antibody (clone Rmut5) | ELISA, FC | Chimeric (mouse/human) IgG |
MRO-0288-CN | Rabbit Anti-MS4A1 Recombinant Antibody (clone CBACN-109) | WB, IHC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
HPAB-0683-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut8); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
HPAB-0684-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone Rmut5); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
HPAB-0742-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0742-CN-F(E)) | ELISA, FC | Human Fab |
HPAB-0743-CN-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0743-CN-F(E)) | ELISA, FC | Human Fab |
HPAB-0247-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone EM201); Fab Fragment | Inhib, ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
AFC-TAB-772 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-016 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-028 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-207 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-771 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
HPAB-1336-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1336-FY-F(E)) | FC, ELISA | Human Fab |
HPAB-1337-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1337-FY-F(E)) | ELISA | Mouse Fab |
HPAB-1775-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1775-FY-F(E)) | ELISA, Activ | Mouse Fab |
HPAB-1885-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1885-FY-F(E)) | ELISA, FC | Human Fab |
HPAB-1954-FY-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone BD31-7); scFv Fragment | Cyt | Humanized scFv |
Submit a review or a question
There are currently no Customer reviews or questions for PABX-028. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.